Characterization of the decision-making deficit of patients with ventromedial prefrontal cortex lesions
On a gambling task that models real-life decisions, patients with bilateral lesions of the
ventromedial prefrontal cortex (VM) opt for choices that yield high immediate gains in spite of …
ventromedial prefrontal cortex (VM) opt for choices that yield high immediate gains in spite of …
Decision-making and addiction (part II): myopia for the future or hypersensitivity to reward?
On a decision-making instrument known as the “gambling task”(GT), a subgroup of
substance dependent individuals (SDI) opted for choices that yield high immediate gains in …
substance dependent individuals (SDI) opted for choices that yield high immediate gains in …
Electrophysiological correlates of reward prediction error recorded in the human prefrontal cortex
Lesion and functional imaging studies have shown that the ventromedial prefrontal cortex is
critically involved in the avoidance of risky choices. However, detailed descriptions of the …
critically involved in the avoidance of risky choices. However, detailed descriptions of the …
Decision-making and addiction (part I): impaired activation of somatic states in substance dependent individuals when pondering decisions with negative future …
A Bechara, H Damasio - Neuropsychologia, 2002 - Elsevier
Some substance dependent individuals (SDI) suffer from a decision-making impairment akin
to that seen in neurological patients with lesions of the ventromedial (VM) prefrontal cortex …
to that seen in neurological patients with lesions of the ventromedial (VM) prefrontal cortex …
Neurobiology of decision-making: risk and reward.
A Bechara - Seminars in clinical neuropsychiatry, 2001 - europepmc.org
Neurological patients with bilateral ventromedial (VM) lesions of the prefrontal cortex often
deny, or they are not aware that they have a problem. Furthermore, they often pursue actions …
deny, or they are not aware that they have a problem. Furthermore, they often pursue actions …
Differential effects of insular and ventromedial prefrontal cortex lesions on risky decision-making
The ventromedial prefrontal cortex (vmPFC) and insular cortex are implicated in distributed
neural circuitry that supports emotional decision-making. Previous studies of patients with …
neural circuitry that supports emotional decision-making. Previous studies of patients with …
Phineas gauged: decision-making and the human prefrontal cortex
Poor social judgment and decision-making abilities have often been attributed to people
who have suffered injury to the ventromedial prefrontal cortex (VMPFC). However, few …
who have suffered injury to the ventromedial prefrontal cortex (VMPFC). However, few …
Failure to respond autonomically to anticipated future outcomes following damage to prefrontal cortex
Following damage to specific sectors of the prefrontal cortex, humans develop a defect in
real-life decision making, in spite of otherwise normal intellectual performance. The patients …
real-life decision making, in spite of otherwise normal intellectual performance. The patients …
Impulsivity and risk-taking behavior in focal frontal lobe lesions
Frontal lobe dysfunction may underlie excessively impulsive and risky behavior observed in
a range of neurological disorders. We devised a gambling task to examine these behavior …
a range of neurological disorders. We devised a gambling task to examine these behavior …
Insensitivity to future consequences following damage to human prefrontal cortex
A Bechara, AR Damasio, H Damasio, SW Anderson - Cognition, 1994 - Elsevier
Following damage to the ventromedial prefrontal cortex, humans develop a defect in real-life
decision-making, which contrasts with otherwise normal intellectual functions. Currently …
decision-making, which contrasts with otherwise normal intellectual functions. Currently …