The value of antimicrobial peptides in the age of resistance

M Magana, M Pushpanathan, AL Santos… - The lancet infectious …, 2020 - thelancet.com
Accelerating growth and global expansion of antimicrobial resistance has deepened the
need for discovery of novel antimicrobial agents. Antimicrobial peptides have clear …

Antimicrobial peptides

M Malmsten - Upsala journal of medical sciences, 2014 - Taylor & Francis
With increasing antibiotics resistance, there is an urgent need for novel infection
therapeutics. Since antimicrobial peptides provide opportunities for this, identification and …

A new era of antibiotics: the clinical potential of antimicrobial peptides

K Browne, S Chakraborty, R Chen… - International journal of …, 2020 - mdpi.com
Antimicrobial resistance is a multifaceted crisis, imposing a serious threat to global health.
The traditional antibiotic pipeline has been exhausted, prompting research into alternate …

[HTML][HTML] Antimicrobial peptide mimics for clinical use: does size matter?

J Svenson, N Molchanova, CI Schroeder - Frontiers in Immunology, 2022 - frontiersin.org
The search for efficient antimicrobial therapies that can alleviate suffering caused by
infections from resistant bacteria is more urgent than ever before. Infections caused by multi …

Antimicrobial peptides: an overview of a promising class of therapeutics

A Giuliani, G Pirri, S Nicoletto - Open Life Sciences, 2007 - degruyter.com
Antibiotic resistance is increasing at a rate that far exceeds the pace of new development of
drugs. Antimicrobial peptides, both synthetic and from natural sources, have raised interest …

Lights and shadows on the therapeutic use of antimicrobial peptides

D Bellotti, M Remelli - Molecules, 2022 - mdpi.com
The emergence of antimicrobial-resistant infections is still a major concern for public health
worldwide. The number of pathogenic microorganisms capable of resisting common …

Strategies for the discovery and advancement of novel cationic antimicrobial peptides

EB Hadley, R EW Hancock - Current topics in medicinal …, 2010 - ingentaconnect.com
Multi-drug resistant bacteria are appearing at an alarming rate and impose significant
burdens on healthcare systems worldwide. Cationic peptides have shown great promise as …

Molecular engineering of antimicrobial peptides: Microbial targets, peptide motifs and translation opportunities

P Cardoso, H Glossop, TG Meikle, A Aburto-Medina… - Biophysical …, 2021 - Springer
The global public health threat of antimicrobial resistance has led the scientific community to
highly engage into research on alternative strategies to the traditional small molecule …

Antimicrobial peptides as anti-infective agents in pre-post-antibiotic era?

T Rončević, J Puizina, A Tossi - International journal of molecular …, 2019 - mdpi.com
Resistance to antibiotics is one of the main current threats to human health and every year
multi-drug resistant bacteria are infecting millions of people worldwide, with many dying as a …

Antimicrobial peptides—Mechanisms of action, antimicrobial effects and clinical applications

J Talapko, T Meštrović, M Juzbašić, M Tomas, S Erić… - Antibiotics, 2022 - mdpi.com
The growing emergence of antimicrobial resistance represents a global problem that not
only influences healthcare systems but also has grave implications for political and …