Cholinergic neuromodulation, a candidate mechanism for aspects of attention, is complex
and is not well understood. Because structure constrains function, quantitative anatomy is an …

Acetylcholine (ACh) is believed to underlie mechanisms of arousal and attention in
mammals. ACh also has a demonstrated functional effect in visual cortex that is both diverse …

Cholinergic neuromodulation is a candidate mechanism for aspects of arousal and attention
in mammals. We have reported previously that cholinergic modulation in the primary visual …

Acetylcholine can have diverse effects on visual cortical neurons as a result of variations in
postsynaptic receptor subtypes as well as the types of neurons and subcellular sites …

Background In the mammalian neocortex, cells that express parvalbumin (PV neurons)
comprise a dominant class of inhibitory neuron that substantially overlaps with the …

Acetylcholine modulates maturation and neuronal activity through muscarinic and nicotinic
receptors in the primary visual cortex. However, the specific contribution of different …

ACh modulates neuronal activity throughout the cerebral cortex, including the primary visual
cortex (V1). However, a number of issues regarding this modulation remain unknown, such …

The central cholinergic system plays a crucial role in synaptic plasticity and spatial attention;
however, the roles of the individual cholinergic receptors involved in these activities are not …

Muscarinic cholinergic transmission plays an important role in modulating hippocampal
activity and many higher brain functions. Many of the modulatory effects of acetylcholine on …

Acetylcholine (ACh) has been implicated in selective attention. To understand the local
circuit action of ACh, we iontophoresed cholinergic agonists into the primate primary visual …