Background Resistance to cell death, a protective mechanism for removing damaged cells,
is a “Hallmark of Cancer” that is essential for cancer progression. Increasing attention to …

Cancer cells frequently display fundamentally altered cellular metabolism, which provides
the biochemical foundation and directly contributes to tumorigenicity and malignancy …

Increased lipogenesis is a hallmark of a wide variety of cancers and is under intense
investigation as potential antineoplastic target. Although brisk lipogenesis is observed in the …

To proliferate, metastasize, or resist stress conditions imposed by the microenvironment,
many cancer cells rely on fatty acid β-oxidation to generate acetyl-CoA and fuel the TCA …

Deregulated cell proliferation is an established feature of cancer, and altered tumor
metabolism has witnessed renewed interest over the past decade, including the study of …

Simple Summary Metabolic reprogramming is gaining attentions as a hallmark of cancers.
However, lipid metabolism has been difficult to analyze due to technical problems. In recent …

With the advent of effective tools to study lipids, including mass spectrometry-based
lipidomics, lipids are emerging as central players in cancer biology. Lipids function as …

Fatty acid metabolism is known to support tumorigenesis and disease progression as well
as treatment resistance through enhanced lipid synthesis, storage and catabolism. More …

Cancer cells rely on several metabolic pathways such as lipid metabolism to meet the
increase in energy demand, cell division, and growth and successfully adapt to challenging …

Metastasis is the most malignant stage of cancer. Lipid metabolic abnormalities are now
increasingly recognized as characteristics of cancer cells. The accumulation of certain lipid …