Background Thymoquinone (TQ), an active compound isolated from Nigella sativa, has
been proven to exhibit various biological properties such as antioxidant. Although oral …

Background Thymoquinone (TQ), the predominant active lipophilic component in Nigella
sativa seed oil, has a variety of pharmacological properties such as anticancer activities …

Background Nanostructured lipid carriers (NLCs), composed of solid and liquid lipids, and
surfactants are potentially good colloidal drug carriers. Thymoquinone is the main bioactive …

Thymoquinone (TQ), obtained from black cumin (Nigella sativa), is a natural product with
anti-oxidant, anti-inflammatory, and hepatoprotective effects but unfortunately with poor …

Thymoquinone (TQ) has been shown to exhibit antitumor properties. Thymoquinone‐loaded
nanostructured lipid carrier (TQ‐NLC) was developed to improve the bioavailability and …

High lipophilicity, low bioavailability, and hostile gastrointestinal (GI) environment is the
major concern in oral administration of thymoquinone (TQ). Herein, we developed chitosan …

Thymoquinone (TQ), a bioactive compound found in Nigella sativa, cannot be orally
consumed due to its lipophilicity. In order to overcome this low bioavailability, TQ is loaded …

ABSTRACT Introduction: Thymoquinone (TQ), 2-isopropyl-5-methylbenzo-1, 4-quinone, the
main active constituent of Nigella sativa (NS) plant, has been proven to be of great …

Thymoquinone, a well-known phytoconstituent derived from the seeds of Nigella sativa,
exhibits unique pharmacological activities However, despite the various medicinal …

Background: The poor biopharmaceutical properties of thymoquinone (TQ) obstruct its
development as a hepatoprotective agent. To surmount the delivery challenges of TQ …