The hypertensive myocardium: from microscopic lesions to clinical complications and outcomes

MU Moreno, R Eiros, JJ Gavira, C Gallego… - Medical …, 2017 - medical.theclinics.com
The heart is very sensitive to physiologic stimuli or pathologic states, and even slight
perturbations may lead to severe cardiac changes, eventually with detrimental outcomes …

The progression of hypertensive heart disease

MH Drazner - Circulation, 2011 - Am Heart Assoc
Hypertensive heart disease is a constellation of abnormalities that includes left ventricular
hypertrophy (LVH), systolic and diastolic dysfunction, and their clinical manifestations …

Hypertensive heart disease

J Díez - 2013 - Taylor & Francis
From a pathophysiological viewpoint, hypertensive heart disease (HHD) can be defined as
the cardiomyopathy that results from the response of the myocardium to the biomechanical …

A translational approach to hypertensive heart disease

J Díez, ED Frohlich - Hypertension, 2010 - Am Heart Assoc
The spectrum of the cardiac complications of arterial hypertension includes heart failure
(HF), sudden death, and cardiac dysrhythmias, as well as the exacerbation of coincidental …

Hypertensive Heart Disease: A Narrative Review Series—Part 2: Macrostructural and Functional Abnormalities

V Nemtsova, T Burkard, AS Vischer - Journal of Clinical Medicine, 2023 - mdpi.com
Hypertensive heart disease (HHD) remains a major global public health concern despite the
implementation of new approaches for the management of hypertensive patients. The …

Pathophysiology of hypertensive heart disease: beyond left ventricular hypertrophy

CC Nwabuo, RS Vasan - Current hypertension reports, 2020 - Springer
Abstract Purpose of Review Given that the life expectancy and the burden of hypertension
are projected to increase over the next decade, hypertensive heart disease (HHD) may be …

Transition to heart failure in hypertension: going to the heart of the matter

A Bayés-Genís, J Díez - European heart journal, 2022 - academic.oup.com
Heart failure (HF) affects up to one in five adults during their lifetime and is associated with
considerable mortality and morbidity, despite advances in management. Although most of …

Growing heart failure burden of hypertensive heart disease: a call to action

J Díez, J Butler - Hypertension, 2023 - Am Heart Assoc
Hypertensive heart disease (HHD) is currently the second leading cause of heart failure. The
prevalence of HHD and its associated risk of heart failure have increased despite substantial …

Hypertensive heart disease: a narrative review series—part 1: pathophysiology and microstructural changes

V Nemtsova, AS Vischer, T Burkard - Journal of clinical medicine, 2023 - mdpi.com
Sustained hypertension causes structural, functional, and neurohumoral abnormalities in the
heart, a disease commonly termed hypertensive heart disease (HHD). Modern concepts of …

Mechanisms and management of hypertensive heart disease: from left ventricular hypertrophy to heart failure

JL Izzo, AH Gradman - Medical Clinics, 2004 - medical.theclinics.com
Hypertensive heart disease (HHD) is a spectrum of abnormalities that represents the
accumulation of a lifetime of functional and structural adaptations to increased blood …