The paradigm of platelets as mere mediators of hemostasis has long since been replaced by
a dual role: hemostasis and inflammation. Now recognized as key players in innate and …

Platelets are anucleate blood cells, long known to be critically involved in hemostasis and
thrombosis. In addition to their role in blood clots, increasing evidence reveals significant …

Platelets occupy a central role at the interface between thrombosis and inflammation. At
sites of vascular damage, adherent platelets physically and functionally interact with …

Although the function of platelets in the maintenance of hemostasis has been studied in
great detail, more recent evidence has highlighted a central role for platelets in the host …

Although platelets are traditionally recognized for their central role in hemostasis, many lines
of research clearly demonstrate these rather ubiquitous blood components are potent …

Platelets are chief effector cells in hemostasis. In addition, they are multifaceted
inflammatory cells with functions that span the continuum from innate immune responses to …

Platelets are the main players in thrombosis and hemostasis; however they also play
important roles during inflammation and infection. Through their surface receptors, platelets …

Despite their small size and anucleate status, platelets have diverse roles in vascular
biology. Not only are platelets the cellular mediator of thrombosis, but platelets are also …

Systemic inflammatory responses are associated with high morbidity and mortality and
represent a diverse and clinically challenging group of diseases. Platelets are increasingly …

Platelets, non-nucleated blood components first described over 130 years ago, are
recognized as the primary cell regulating hemostasis and thrombosis. The vascular …