Immunoregulation of bone marrow‐derived mesenchymal stem cells on the chronic cigarette smoking‐induced lung inflammation in rats
X Li, J Wang, J Cao, L Ma, J Xu - BioMed Research …, 2015 - Wiley Online Library
Impact of bone mesenchymal stem cell (BMSC) transfusion on chronic smoking‐induced
lung inflammation is poorly understood. In this study, a rat model of smoking‐related lung …
lung inflammation is poorly understood. In this study, a rat model of smoking‐related lung …
TNF‐α‐induced NF‐κB activation promotes myofibroblast differentiation of LR‐MSCs and exacerbates bleomycin‐induced pulmonary fibrosis
J Hou, T Ma, H Cao, Y Chen, C Wang… - Journal of cellular …, 2018 - Wiley Online Library
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and irreversible lung disease of
unknown cause. It has been reported that both lung resident mesenchymal stem cells (LR …
unknown cause. It has been reported that both lung resident mesenchymal stem cells (LR …
Immunomodulation by therapeutic mesenchymal stromal cells (MSC) is triggered through phagocytosis of MSC by monocytic cells
SFH de Witte, F Luk, JM Sierra Parraga, M Gargesha… - stem cells, 2018 - academic.oup.com
Mesenchymal stem or stromal cells (MSC) are under investigation as a potential
immunotherapy. MSC are usually administered via intravenous infusion, after which they are …
immunotherapy. MSC are usually administered via intravenous infusion, after which they are …
Comparison of epithelial differentiation and immune regulatory properties of mesenchymal stromal cells derived from human lung and bone marrow
Mesenchymal stromal cells (MSCs) reside in many organs including lung, as shown by their
isolation from fetal lung tissues, bronchial stromal compartment, bronchial-alveolar lavage …
isolation from fetal lung tissues, bronchial stromal compartment, bronchial-alveolar lavage …
Lung fibrosis is improved by extracellular vesicles from IFNγ-primed mesenchymal stromal cells in murine systemic sclerosis
Background: Systemic sclerosis (SSc) is a severe autoimmune disease for which
mesenchymal stromal cells (MSCs)-based therapy was reported to reduce SSc-related …
mesenchymal stromal cells (MSCs)-based therapy was reported to reduce SSc-related …
Transcriptional profiling of circulating mononuclear cells from patients with chronic obstructive pulmonary disease receiving mesenchymal stromal cell infusions
JD Armitage, DBA Tan, M Sturm… - Stem Cells …, 2021 - academic.oup.com
Chronic obstructive pulmonary disease (COPD) is an inflammatory airways disease with
limited therapeutic options. We have previously shown that mesenchymal stromal cell (MSC) …
limited therapeutic options. We have previously shown that mesenchymal stromal cell (MSC) …
Interpreting immunoregulation in lung fibrosis: a new branch of the immune model
F Huaux - Frontiers in Immunology, 2021 - frontiersin.org
Immunostimulation is recognized as an important contribution in lung fibrosis in some
animal models and patient subsets. With this review, we illustrate an additional scenario …
animal models and patient subsets. With this review, we illustrate an additional scenario …
Current therapeutic strategies for respiratory diseases using mesenchymal stem cells
Mesenchymal stromal/stem cells (MSCs) have a great potential to proliferate, undergo multi‐
directional differentiation, and exert immunoregulatory effects. There is already much …
directional differentiation, and exert immunoregulatory effects. There is already much …
Peripheral blood myeloid-derived suppressor cells reflect disease status in idiopathic pulmonary fibrosis
IE Fernandez, FR Greiffo… - European …, 2016 - Eur Respiratory Soc
Idiopathic pulmonary fibrosis (IPF) is a fibroproliferative disease with irreversible lung
function loss and poor survival. Myeloid-derived suppressor cells (MDSC) are associated …
function loss and poor survival. Myeloid-derived suppressor cells (MDSC) are associated …
Human umbilical cord mesenchymal stromal cells attenuate pulmonary fibrosis via regulatory T cell through interaction with macrophage
Z Tang, J Gao, J Wu, G Zeng, Y Liao, Z Song… - Stem Cell Research & …, 2021 - Springer
Background Pulmonary fibrosis (PF) is a growing clinical problem with limited therapeutic
options. Human umbilical cord mesenchymal stromal cell (hucMSC) therapy is being …
options. Human umbilical cord mesenchymal stromal cell (hucMSC) therapy is being …