Therapeutic administration of bone marrow‐derived mesenchymal stromal cells reduces airway inflammation without up‐regulating Tregs in experimental asthma
JZ Kitoko, LL De Castro, AP Nascimento… - Clinical & …, 2018 - Wiley Online Library
Background Prophylactic administration of mesenchymal stromal cells (MSC s) derived from
adipose (AD‐MSC) and bone marrow tissue (BM‐MSC) in ovalbumin‐induced asthma …
adipose (AD‐MSC) and bone marrow tissue (BM‐MSC) in ovalbumin‐induced asthma …
Functional characterisation of bone marrow-derived mesenchymal stromal cells from COPD patients
W Broekman, H Roelofs, MC Zarcone… - ERJ Open …, 2016 - Eur Respiratory Soc
Autologous bone marrow-derived mesenchymal stromal cells (BM-MSCs) are evaluated for
clinical use in chronic obstructive pulmonary disease (COPD) patients, but it is unclear …
clinical use in chronic obstructive pulmonary disease (COPD) patients, but it is unclear …
Acute and chronic effects of treatment with mesenchymal stromal cells on LPS-induced pulmonary inflammation, emphysema and atherosclerosis development
PPSJ Khedoe, S de Kleijn, AM van Oeveren-Rietdijk… - PLoS …, 2017 - journals.plos.org
Background COPD is a pulmonary disorder often accompanied by cardiovascular disease
(CVD), and current treatment of this comorbidity is suboptimal. Systemic inflammation in …
(CVD), and current treatment of this comorbidity is suboptimal. Systemic inflammation in …
Clinical applications of mesenchymal stem cells in chronic lung diseases
KM Antoniou, K Karagiannis, E Tsitoura… - Biomedical …, 2018 - spandidos-publications.com
Mesenchymal stem (stromal) cells (MSCs) are multipotent stromal cells that have the ability
to modulate immune response to tissue injury and promote repair in vivo. The therapeutic …
to modulate immune response to tissue injury and promote repair in vivo. The therapeutic …
Bone marrow-derived mesenchymal stromal cells (MSCs) modulate the inflammatory character of alveolar macrophages from sarcoidosis patients
I McClain Caldwell, C Hogden, K Nemeth… - Journal of clinical …, 2020 - mdpi.com
Sarcoidosis is a devastating inflammatory disease affecting many organs, especially the
lungs and lymph nodes. Bone marrow-derived mesenchymal stromal cells (MSCs) can …
lungs and lymph nodes. Bone marrow-derived mesenchymal stromal cells (MSCs) can …
Strategies to improve the therapeutic effects of mesenchymal stromal cells in respiratory diseases
LHA Silva, MA Antunes, CC Dos Santos… - Stem Cell Research & …, 2018 - Springer
Due to their anti-inflammatory, antiapoptotic, antimicrobial, and antifibrotic properties,
mesenchymal stromal cells (MSCs) have been considered a promising alternative for …
mesenchymal stromal cells (MSCs) have been considered a promising alternative for …
Paracrine factors from mesenchymal stem cells attenuate epithelial injury and lung fibrosis
Q Shen, B Chen, Z Xiao, L Zhao… - Molecular …, 2015 - spandidos-publications.com
Paracrine factors are currently considered to be the major mechanism through which
mesenchymal stem cells (MSCs) exert their actions. The aim of this study was to investigate …
mesenchymal stem cells (MSCs) exert their actions. The aim of this study was to investigate …
Endothelial progenitor cells as a potential biomarker in interstitial lung disease associated with rheumatoid arthritis
V Pulito-Cueto, S Remuzgo-Martínez, F Genre… - Journal of Clinical …, 2020 - mdpi.com
Interstitial lung disease (ILD) increases morbidity and mortality in patients with rheumatoid
arthritis (RA). Although the pathogenesis of ILD associated with RA (RA-ILD+) remains …
arthritis (RA). Although the pathogenesis of ILD associated with RA (RA-ILD+) remains …
Activation of human mesenchymal stem cells impacts their therapeutic abilities in lung injury by increasing interleukin (IL)-10 and IL-1RN levels
ML Bustos, L Huleihel, EM Meyer… - Stem cells …, 2013 - academic.oup.com
Acute respiratory distress syndrome (ARDS) is an important cause of morbidity and mortality,
with no currently effective therapies. Several preclinical studies have shown that human …
with no currently effective therapies. Several preclinical studies have shown that human …
Evidence for a functional thymic stromal lymphopoietin signaling axis in fibrotic lung disease
A Datta, R Alexander, MG Sulikowski… - The Journal of …, 2013 - journals.aai.org
Thymic stromal lymphopoietin (TSLP) recently has emerged as a key cytokine in the
development of type 2 immune responses. Although traditionally associated with allergic …
development of type 2 immune responses. Although traditionally associated with allergic …