Synthesis and biological evaluation of some new 1, 4-dihydropyridines containing different ester substitute and diethyl carbamoyl group as anti-tubercular agents

M Khoshneviszadeh, N Edraki, K Javidnia… - Bioorganic & Medicinal …, 2009 - Elsevier
Tuberculosis is a leading infectious cause of death worldwide. Because of the concern of the
resistance to most of the commonly used drugs displayed by the considered mycobacteria …

Synthesis and Biological Evaluation of Some Novel 1, 4‐Dihydropyridines as Potential AntiTubercular Agents

A Trivedi, D Dodiya, B Dholariya… - Chemical Biology & …, 2011 - Wiley Online Library
Recent studies showed that 1, 4‐dihydropyridine‐3, 5‐dicarbamoyl derivatives with
lipophilic groups have significant antitubercular activity. In this study, we have synthesized …

Synthesis and biological evaluation of some novel N-aryl-1, 4-dihydropyridines as potential antitubercular agents

AR Trivedi, DK Dodiya, BH Dholariya… - Bioorganic & medicinal …, 2011 - Elsevier
1, 4-Dihydropyridines are the emerging class of antitubercular agent. Recently, studies have
revealed that 1, 4-dihydropyridine-3, 5-dicarbamoyl derivatives with lipophilic groups have …

Synthesis and antitubercular activity of new N, N-diaryl-4-(4, 5-dichloroimidazole-2-yl)-1, 4-dihydro-2, 6-dimethyl-3, 5-pyridinedicarboxamides

M AMINI, PL NAVID, A SHAFIEI - 2008 - sid.ir
Background and the purpose of the study: DIHYDROPYRIDINE s having carboxamides in 3
and 5 positions show anti-tuberculosis activity. The purpose of the present study was to …

Design, synthesis, and biological evaluation of 1, 4‐dihydropyridine derivatives as potent antitubercular agents

NC Desai, AR Trivedi, HC Somani… - Chemical Biology & …, 2015 - Wiley Online Library
A series of novel 1, 4‐dihydropyridine‐3, 5‐dicarbamoyl derivatives bearing an imidazole
nucleus at C‐4 position were synthesized in excellent yields via multicomponent Hantzsch …

Synthesis and QSAR studies of 4-substituted phenyl-2, 6-dimethyl-3, 5-bis-N-(substituted phenyl) carbamoyl-1, 4-dihydropyridines as potential antitubercular agents

B Desai, D Sureja, Y Naliapara, A Shah… - Bioorganic & medicinal …, 2001 - Elsevier
Synthesis and QSAR studies of the title compounds have resulted in the identification of
structural and physicochemical parameters (MR, σo, σm, σp) contributing to antitubercular …

Synthesis and antitubercular activity of novel 4-substituted imidazolyl-2, 6-dimethyl-N3, N5-bisaryl-1, 4-dihydropyridine-3, 5-dicarboxamides

A Fassihi, Z Azadpour, N Delbari, L Saghaie… - European Journal of …, 2009 - Elsevier
A series of 4-substituted imidazolyl-2, 6-dimethyl-N3, N5-bisaryl-1, 4-dihydropyridine-3, 5-
dicarboxamides were prepared. They were screened as antitubercular agents against …

[PDF][PDF] Synthesis, antitubercular, antifungal and antibacterial activities of 6-substituted phenyl-2-(3'-Substituted Phenyl Pyridazin-6'-yl)-2, 3, 4, 5-tetrahydropyridazin-3 …

M Islam, AA Siddiqui, R Rajesh - Acta Pol Pharm, 2008 - ptfarm.pl
A series of 6-substituted phenyl-2-(3í-substituted phenyl pyridazin-6í-yl)-2, 3, 4, 5-
tetrahydropyridazin-3-ones has been synthesized. An appropriate aromatic hydrocarbon …

Synthesis, antibacterial and antimycobacterial activities of some new 4-aryl/heteroaryl-2, 6-dimethyl-3, 5-bis-N-(aryl)-carbamoyl-1, 4-dihydropyridines

K Sirisha, D Bikshapathi, G Achaiah… - European journal of …, 2011 - Elsevier
A novel class of 4-aryl/heteroaryl-2, 6-dimethyl-3, 5-bis-N-(phenyl/substituted phenyl)-
carbamoyl-1, 4-dihydropyridines has been synthesized by simple, economical and eco …

Synthesis and biological evaluation of substituted 4, 6-diarylpyrimidines and 3, 5-diphenyl-4, 5-dihydro-1H-pyrazoles as anti-tubercular agents

V Pathak, HK Maurya, S Sharma, KK Srivastava… - Bioorganic & medicinal …, 2014 - Elsevier
Abstract Various substituted 4, 6-diarylpyrimidin-2-amine (4), 4, 6-diaryl-2-(heteroaryl)
pyrimidine (6) and 1-(3, 5-diaryl-4, 5-dihydro-1H-pyrazol-1-yl) ethanone (7) derivatives were …