Targeting spike glycoprotein S1 mediated by NLRP3 inflammasome machinery and the cytokine releases in A549 lung epithelial cells by nanocurcumin
C Chittasupho, K Srisawad, P Arjsri, R Phongpradist… - Pharmaceuticals, 2023 - mdpi.com
Chronic inflammation and tissue damage can result from uncontrolled inflammation during
SARS-CoV-2 or COVID-19 infections, leading to post-acute COVID conditions or long …
SARS-CoV-2 or COVID-19 infections, leading to post-acute COVID conditions or long …
Nanocurcumin potently inhibits SARS-CoV-2 spike protein-induced cytokine storm by deactivation of MAPK/NF-κB signaling in epithelial cells
VK Sharma, Prateeksha, SP Singh… - ACS Applied Bio …, 2022 - ACS Publications
Interleukin-mediated deep cytokine storm, an aggressive inflammatory response to SARS-
CoV-2 virus infection in COVID-19 patients, is correlated directly with lung injury, multi-organ …
CoV-2 virus infection in COVID-19 patients, is correlated directly with lung injury, multi-organ …
Inhibition of SARS-CoV-2-Induced NLRP3 Inflammasome-Mediated Lung Cell Inflammation by Triphala-Loaded Nanoparticle Targeting Spike Glycoprotein S1
C Chittasupho, S Umsumarng, K Srisawad, P Arjsri… - Pharmaceutics, 2024 - mdpi.com
The COVID-19 pandemic, caused by SARS-CoV-2, poses a significant global health threat.
The spike glycoprotein S1 of the SARS-CoV-2 virus is known to induce the production of pro …
The spike glycoprotein S1 of the SARS-CoV-2 virus is known to induce the production of pro …
Curcuma phaeocaulis Inhibits NLRP3 Inflammasome in Macrophages and Ameliorates Nanoparticle-Induced Airway Inflammation in Mice
YJ Nam, J Choi, JS Lee, C Seo, G Lee, Y Lee, JK Kim… - Molecules, 2022 - mdpi.com
The activation of NLRP3 results in the assembly of inflammasome that regulates caspase-1
activation and the subsequent secretion of bioactive interleukin (IL)-1β. Excessive activation …
activation and the subsequent secretion of bioactive interleukin (IL)-1β. Excessive activation …
N-acetylcysteine reduces inflammasome activation induced by SARS-coV-2 proteins in vitro
J Milara, F Martínez-Expósito, P Montero… - International Journal of …, 2022 - mdpi.com
Inflammasome activation is one of the first steps in initiating innate immune responses. In
this work, we studied the activation of inflammasomes in the airways of critically ill COVID-19 …
this work, we studied the activation of inflammasomes in the airways of critically ill COVID-19 …
Luteolin-rich fraction from Perilla frutescens seed meal inhibits spike glycoprotein S1 of SARS-CoV-2-induced NLRP3 inflammasome lung cell inflammation via …
S Dissook, S Umsumarng, S Mapoung… - Frontiers in …, 2023 - frontiersin.org
Objective The multi-systemic inflammation as a result of COVID-19 can persevere long after
the initial symptoms of the illness have subsided. These effects are referred to as Long …
the initial symptoms of the illness have subsided. These effects are referred to as Long …
COVID‐19: A case for inhibiting NLRP3 inflammasome, suppression of inflammation with Curcumin?
A Saeedi‐Boroujeni… - Basic & Clinical …, 2021 - Wiley Online Library
Curcumin is the effective ingredient of turmeric, sometimes used as a painkiller in traditional
medicine. It has extensive biological properties such as anti‐inflammatory and antioxidant …
medicine. It has extensive biological properties such as anti‐inflammatory and antioxidant …
Curcumin represses NLRP3 inflammasome activation via TLR4/MyD88/NF-κB and P2X7R signaling in PMA-induced macrophages
F Kong, B Ye, J Cao, X Cai, L Lin, S Huang… - Frontiers in …, 2016 - frontiersin.org
Aims: In the NOD-like receptor (NLR) family, the pyrin domain containing 3 (NLRP3)
inflammasome is closely related to the progression of atherosclerosis. This study aimed to …
inflammasome is closely related to the progression of atherosclerosis. This study aimed to …
Nano-curcumin therapy, a promising method in modulating inflammatory cytokines in COVID-19 patients
H Valizadeh, S Abdolmohammadi-Vahid… - International …, 2020 - Elsevier
Background As an ongoing worldwide health issue, Coronavirus disease 2019 (COVID–19)
has been causing serious complications, including pneumonia, acute respiratory distress …
has been causing serious complications, including pneumonia, acute respiratory distress …
Curcumin ameliorates monosodium urate‐induced gouty arthritis through Nod‐like receptor 3 inflammasome mediation via inhibiting nuclear factor‐kappa B signaling
X Li, DQ Xu, DY Sun, T Zhang, X He… - Journal of Cellular …, 2019 - Wiley Online Library
Background Monosodium urate (MSU) crystals‐induced inflammation is a key initiator in
gouty arthritis. Curcumin is an active ingredient possessing anti‐inflammatory efficacy. But …
gouty arthritis. Curcumin is an active ingredient possessing anti‐inflammatory efficacy. But …
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