Identifying potential drug targets in hepatocellular carcinoma based on network analysis and one-class support vector machine
Z Tong, Y Zhou, J Wang - Scientific reports, 2019 - nature.com
Hepatocellular carcinoma (HCC) is one major cause of cancer-related death worldwide. But
now, the systematic therapy for the advanced stages of HCC is rather limited. Thus, the …
now, the systematic therapy for the advanced stages of HCC is rather limited. Thus, the …
Combined transcriptomics and in-silico approach uncovers the role of prognostic biomarkers in hepatocellular carcinoma
Liver cancer is among the top five death-causing malignancies. High mortality rate, poor
prognosis, and minimal drug options for hepatocellular carcinoma (HCC) patients led to the …
prognosis, and minimal drug options for hepatocellular carcinoma (HCC) patients led to the …
[HTML][HTML] An immune and epigenetics-related scoring model and drug candidate prediction for hepatic carcinogenesis via dynamic network biomarker analysis and …
Y Hu, X Zhang, Q Li, Q Zhou, D Fang, Y Lu - Computational and Structural …, 2023 - Elsevier
Hepatocellular carcinoma (HCC) is a malignant tumor with high mortality. This study aimed
to build a prognostic signature for HCC patients based on immune-related genes (IRGs) and …
to build a prognostic signature for HCC patients based on immune-related genes (IRGs) and …
Identification of drug targets and agents associated with hepatocellular carcinoma through integrated bioinformatics analysis
Background: Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related
death globally. The mechanisms underlying the development of HCC are mostly unknown …
death globally. The mechanisms underlying the development of HCC are mostly unknown …
Predicting therapeutic drugs for hepatocellular carcinoma based on tissue-specific pathways
L Yu, M Wang, Y Yang, F Xu, X Zhang… - PLoS Computational …, 2021 - journals.plos.org
Hepatocellular carcinoma (HCC) is a significant health problem worldwide with poor
prognosis. Drug repositioning represents a profitable strategy to accelerate drug discovery …
prognosis. Drug repositioning represents a profitable strategy to accelerate drug discovery …
[HTML][HTML] Identification of potential therapeutic targets in hepatocellular carcinoma using an integrated bioinformatics approach
Q Huang, J Li, A Wei - Translational Cancer Research, 2018 - tcr.amegroups.org
Background: Hepatocellular carcinoma (HCC) frequently recurs and has poor prognosis,
and thus it is essential to investigate the molecular mechanisms associated with HCC …
and thus it is essential to investigate the molecular mechanisms associated with HCC …
Predict new therapeutic drugs for hepatocellular carcinoma based on gene mutation and expression
L Yu, F Xu, L Gao - Frontiers in Bioengineering and Biotechnology, 2020 - frontiersin.org
Hepatocellular carcinoma (HCC) is the fourth most common primary liver tumor and is an
important medical problem worldwide. However, the use of current therapies for HCC is no …
important medical problem worldwide. However, the use of current therapies for HCC is no …
Identification of core genes and outcomes in hepatocellular carcinoma by bioinformatics analysis
S Shen, J Kong, Y Qiu, X Yang… - Journal of cellular …, 2019 - Wiley Online Library
Hepatocellular carcinoma (HCC) is the most common malignant liver disease in the world.
However, the mechanistic relationships among various genes and signaling pathways are …
However, the mechanistic relationships among various genes and signaling pathways are …
Bioinformatics identification of crucial genes and pathways associated with hepatocellular carcinoma
X Gao, X Wang, S Zhang - Bioscience reports, 2018 - portlandpress.com
Hepatocellular carcinoma (HCC) is a major cause of cancer-related death worldwide. Up to
date, HCC pathogenesis has not been fully understood. The aim of the present study was to …
date, HCC pathogenesis has not been fully understood. The aim of the present study was to …
In Silico Identification of Crucial Genes and Specific Pathways in Hepatocellular Cancer
Y Sun, Z Zhang - Genetic Testing and Molecular Biomarkers, 2020 - liebertpub.com
Background: Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related
deaths worldwide. Patients suffering from HCC are usually diagnosed during an advanced …
deaths worldwide. Patients suffering from HCC are usually diagnosed during an advanced …
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