Abstract DDX5 and DDX17 are DEAD-box RNA helicase paralogs which regulate several
aspects of gene expression, especially transcription and splicing, through incompletely …

Inducible transcriptional elongation is a rapid, stereotypic mechanism for activating
immediate early immune defense genes by the epithelium in response to viral pathogens …

Abstract RNA helicases DDX5 and DDX17 are multitasking proteins that regulate gene
expression in different biological contexts through diverse activities. Special attention has …

The human DEAD-box protein DDX3X is an RNA remodelling enzyme that has been
implicated in various aspects of RNA metabolism. In addition, like many DEAD-box proteins …

DDX3 belongs to the DEAD‐box proteins, a large family of ATP‐dependent RNA helicases
that participate in all aspects of RNA metabolism. Human DDX3 is a component of several …

Ded1 is a DEAD-box RNA helicase with essential roles in translation initiation. It binds to the
eukaryotic initiation factor 4F (eIF4F) complex and promotes 48S preinitiation complex …

In eukaryotic organisms, the orthologs of the DEAD-box RNA helicase Ded1p from yeast
and DDX3 from human form a well-defined subfamily that is characterized by high sequence …

Among the proteins predicted to be a part of the DExD box RNA helicase family, the
functions of DDX49 are unknown. Here, we characterize the enzymatic activities and …

DDX3X is a conserved DEAD-box RNA helicase involved in translation initiation and other
processes of RNA metabolism. Mutations in human DDX3X and deregulation of its …

DDX3 (or Ded1p), the highly conserved subfamily of the DEAD-box RNA helicase family (40
members in humans), plays important roles in RNA metabolism. DDX3X and DDX3Y, the …