Metformin is the first line therapy of type 2 diabetics, but continued reduction of their life
expectancy warrants further investigation into alternative treatment strategies. This study …

Rooibos, an endemic South African plant, known for its use as herbal tea, has potential as
an antidiabetic herbal product, following recent demonstration of the glucose lowering effect …

Purpose Although several researches have demonstrated that rooibos extract has
hypoglycemic effect, the role of aspalathin, a main polyphenol in the extract, remains …

Effects of aspalathin, a green rooibos tea component, on glucose metabolism were studied
in vitro and in vivo. We first examined the effect of aspalathin on glucose uptake by cultured …

Oral therapeutics used to treat type 2 diabetes and cardiovascular disease often fail to
prevent the progression of disease and their comorbidities. Rooibos (Aspalathus linearis) …

Osthole is an agent isolated from Cnidium monnieri (L.) Cusson and Angelica pubescens
and has been used to treat several diseases, including metabolic syndromes. To investigate …

Type 2 diabetes mellitus (T2DM) is a systemic metabolic disorder characterized by insulin
deficiency and insulin resistance. Recently, it has become a significant threat to public …

Ethanolic extract obtained from Annona cherimola Miller (EEAc) and the flavonoid rutin (Rut)
were evaluated in this study to determine their antihyperglycemic content,% HbA1c …

Objectives Trilobatin, a glycosylated dihydrochalcone, has been reported to have anti-
diabetic properties. However, the underlying mechanism remains unexplained. Methods In …

Aspalathin is a C-glucosyl dihydrochalcone that is abundantly present in Aspalathus
linearis. This endemic South African plant, belonging to the Cape Floristic region, is normally …