[HTML][HTML] Role, molecular mechanism and the potential target of breast cancer stem cells in breast cancer development
T Zhang, H Zhou, K Wang, X Wang, M Wang… - Biomedicine & …, 2022 - Elsevier
Breast cancer (BC) is one of the most common malignant tumors in women globally, and its
occurrence has surpassed lung cancer and become the biggest threat for women. At …
occurrence has surpassed lung cancer and become the biggest threat for women. At …
[HTML][HTML] Breast cancer stem cells
JS Crabtree, L Miele - Biomedicines, 2018 - mdpi.com
Breast cancer stem cells (BCSC) have been implicated in tumor initiation, progression,
metastasis, recurrence, and resistance to therapy. The origins of BCSCs remain …
metastasis, recurrence, and resistance to therapy. The origins of BCSCs remain …
[HTML][HTML] Breast cancer stem cells: Signaling pathways, cellular interactions, and therapeutic implications
Simple Summary Cancer stem cells (CSCs) in breast cancer have been identified for almost
two decades. Many outstanding discoveries have established the important functions of …
two decades. Many outstanding discoveries have established the important functions of …
[HTML][HTML] Signaling pathways governing the maintenance of breast cancer stem cells and their therapeutic implications
A Ordaz-Ramos, O Tellez-Jimenez… - Frontiers in cell and …, 2023 - frontiersin.org
Breast cancer stem cells (BCSCs) represent a distinct subpopulation of cells with the ability
to self-renewal and differentiate into phenotypically diverse tumor cells. The involvement of …
to self-renewal and differentiate into phenotypically diverse tumor cells. The involvement of …
Cancer stem cell in breast cancer therapeutic resistance
Abstract Development of therapeutic resistance and metastasis is a major challenge with
current breast cancer (BC) therapy. Mounting evidence suggests that a subpopulation of …
current breast cancer (BC) therapy. Mounting evidence suggests that a subpopulation of …
[HTML][HTML] Mechanistic pathways of malignancy in breast cancer stem cells
S Yousefnia, F Seyed Forootan… - Frontiers in …, 2020 - frontiersin.org
Breast cancer stem cells (BCSCs) are the minor population of breast cancer (BC) cells that
exhibit several phenotypes such as migration, invasion, self-renewal, and chemotherapy as …
exhibit several phenotypes such as migration, invasion, self-renewal, and chemotherapy as …
Recent developments in targeting breast cancer stem cells (BCSCs): a descriptive review of therapeutic strategies and emerging therapies
K Ali, M Nabeel, F Mohsin, M Iqtedar, M Islam… - Medical Oncology, 2024 - Springer
Despite recent advancements in the diagnosis and treatment of breast cancer (BC), patient
outcomes in terms of survival, recurrence, and disease progression remain suboptimal. A …
outcomes in terms of survival, recurrence, and disease progression remain suboptimal. A …
Breast cancer stem cells, heterogeneity, targeting therapies and therapeutic implications
X Zeng, C Liu, J Yao, H Wan, G Wan, Y Li… - Pharmacological …, 2021 - Elsevier
Both hereditary and sporadic breast cancer are suggested to develop from a stem cell
subcomponent retaining most key stem cell properties but with dysregulation of self-renewal …
subcomponent retaining most key stem cell properties but with dysregulation of self-renewal …
Targeting cellular signaling pathways in breast cancer stem cells and its implication for cancer treatment
BRB Pires, ÍSS DE AMORIM, LDE Souza… - Anticancer …, 2016 - ar.iiarjournals.org
Breast cancer is a public health problem both in developing and developed countries. The
breast cancer stem cell (BCSC) hypothesis has grown in the cancer research community …
breast cancer stem cell (BCSC) hypothesis has grown in the cancer research community …
[HTML][HTML] Breast cancer stem cells: biomarkers, identification and isolation methods, regulating mechanisms, cellular origin, and beyond
Simple Summary Breast cancer stem cells are blamed to be responsible for breast cancer
tumorigenesis, metastasis, drug resistance and tumor recurrence. Therefore, it is critical to …
tumorigenesis, metastasis, drug resistance and tumor recurrence. Therefore, it is critical to …