Recent technological advances, such as the introduction of the direct electron detector, have
transformed the field of cryo-EM and the landscape of molecular and cellular structural …

Electron cryo-microscopy (cryo-EM) is increasingly being used to determine 3D structures of
a broad spectrum of biological specimens from molecules to cells. Anticipating this progress …

The recent resolution revolution in cryo-EM has led to a massive increase in demand for
both time on high-end cryo-electron microscopes and access to cryo-electron microscopy …

Public archiving in structural biology is well established with the Protein Data Bank (PDB;
wwPDB. org) catering for atomic models and the Electron Microscopy Data Bank (EMDB; …

CryoEM in structural biology is currently served by three public archives—EMDB for 3DEM
reconstructions, PDB for models built from 3DEM reconstructions, and EMPIAR for the raw …

Cryogenic electron microscopy (cryo-EM) methods began to be used in the mid-1970s to
study thin and periodic arrays of proteins. Following a half-century of development in cryo …

The MRC binary file format is widely used in the three-dimensional electron microscopy field
for storing image and volume data. Files contain a header which describes the kind of data …

Over the last 5 years what has been called the “Resolution Revolution”(Kühlbrandt, 2014) in
cryo-electron microscopy (cryo-EM) has opened a new era in structural biology. It is now …

The invention of the electron microscope has greatly enhanced the view scientists have of
small structural details. Since its implementation, this technology has undergone …

In discussions at workshops 1, 2 and conferences, the cryo-electron microscopy (EM)
community has repeatedly expressed the need for public archiving of raw 2D image data to …