The activation, proliferation, differentiation, and trafficking of CD4 T cells is central to the
development of type I immune responses. MHC class II (MHCII)-bearing dendritic cells …

Mouse spleen contains three distinct mature dendritic cell (DC) populations (CD4+ 8−,
CD4− 8−, and CD4− 8+) which retain a capacity to take up particulate and soluble Ags …

The activation, differentiation, and subsequent effector functions of CD4 T cells depend on
interactions with a multitude of MHC class II (MHCII)–expressing APCs. To evaluate the …

Antigen-specific B cells express major histocompatibility complex class II and can present
antigen directly to T cells. Adoptive transfer experiments using transgenic B and T cells …

Presentation of MHC class I antigens by professional antigen‐presenting cells (APC) is an
important pathway in priming cytotoxic T lymphocyte responses in vivo. This study sought to …

Dendritic cells (DCs), which maintain tolerance and orchestrate T cell immune responses,
comprise a heterogeneous group of cells. For example, in the steady state, murine spleen …

The activation and differentiation of effector CD4 T cells depends on interactions with MHCII-
expressing antigen presenting cells (APCs). While several APC populations coordinate CD4 …

The relative contributions of different types of antigen presenting cells to T‐cell activation,
expansion and induction of effector functions are still not fully understood. In order to …

We have previously reported that bone marrow derived dendritic cells (DC) pulsed with
major histocompatibility complex (MHC) class I‐restricted peptide efficiently prime a …