Semisynthesis of chondroitin sulfate oligosaccharides based on the enzymatic degradation of chondroitin

X Zhang, H Liu, W Yao, X Meng, Z Li - The Journal of organic …, 2019 - ACS Publications
Chondroitin sulfate (CS) is a structurally complex polyanionic glycosaminoglycan that plays
essential roles in physiological processes. Here we report a facile approach to a library of …

[图书][B] Synthesis and biological activity of chondroitin sulfate biopolymers

SE Tully - 2007 - search.proquest.com
Chondroitin sulfate glycosaminoglycans are ubiquitously expressed linear, sulfated
polysaccharides involved in cell growth, neuronal development and spinal cord injury. The …

Protecting-group-free synthesis of chondroitin 6-sulfate disaccharide and tetrasaccharide

YS Chng, G Tristan, GW Yip, Y Lam - Organic letters, 2019 - ACS Publications
Chondroitin 6-sulfate (CS-C) is an important glycosaminoglycan that regulates many
physiological functions including the development, progression, and metastasis of cancer …

A chondroitin sulfate small molecule that stimulates neuronal growth

SE Tully, R Mabon, CI Gama, SM Tsai… - Journal of the …, 2004 - ACS Publications
Chondroitin sulfate glycosaminoglycans are sulfated polysaccharides involved in cell
division, neuronal development, and spinal cord injury. Here, we report the synthesis and …

Synthesis of chondroitin sulfate oligosaccharides and chondroitin sulfate glycopeptides

S Ramadan, W Yang, X Huang - 2019 - books.rsc.org
Sherif rAmAdANa, b, WeizhuN YANGa ANd Xuefei huANG* a, c, d adepartment of
Chemistry, michigan State university, 578 South Shaw Lane, east Lansing, mi 48824, uSA; …

Enzymatic synthesis of homogeneous chondroitin sulfate oligosaccharides

J Li, G Su, J Liu - Angewandte Chemie International Edition, 2017 - Wiley Online Library
Chondroitin sulfate (CS) is a sulfated polysaccharide that plays essential physiological roles.
Here, we report an enzyme‐based method for the synthesis of a library of 15 different CS …

Semi-synthesis of chondroitin sulfate-E from chondroitin sulfate-A

C Cai, K Solakyildirim, B Yang, JM Beaudet… - Carbohydrate …, 2012 - Elsevier
Chondroitin sulfate-E (chondroitin-4, 6-disulfate) was prepared from chondroitin sulfate-A
(chondroitin-4-sulfate) by regioselective sulfonation, performed using trimethylamine sulfur …

Chondroitin sulfate: structure, function, and biosynthesis

S Nadanaka - Trends in Glycoscience and Glycotechnology, 1999 - jstage.jst.go.jp
Many diseases including infection, inflammation or cancer are caused by the disorder of cell-
cell recognition. Recent studies have unveiled the different roles of chondroitin sulfate (CS) …

Recent advances in the chemical and enzymatic chondroitin sulfate synthesis

A Vibert, JC Jacquinet, C Lopin-Bon - Journal of Carbohydrate …, 2011 - Taylor & Francis
Chondroitin sulfates (CSs) are complex polysaccharides that play important roles in many
biological processes. This mini-review focuses on the recent advances in chemical and …

Sequence determination of synthesized chondroitin sulfate dodecasaccharides

T Shioiri, J Tsuchimoto, H Watanabe, N Sugiura - Glycobiology, 2016 - academic.oup.com
Chondroitin sulfate (CS) is a linear acidic polysaccharide composed of repeating
disaccharide units of glucuronic acid and N-acetyl-d-galactosamine. The polysaccharide is …