Background Assessment of transmural scar at the site of latest mechanical activation is
relevant to maximize outcomes in cardiac resynchronization therapy (CRT). Few studies …

Cardiac resynchronization therapy (CRT) offers proven benefit to patients with refractory
symptomatic chronic heart failure (New York Heart Association Class III or IV), severe left …

Introduction and objectives There is extensive controversy exists on whether cardiac
resynchronization therapy corrects electrical or mechanical asynchrony. The aim of this …

Background Late mechanical activation (LMA) and viability in the left ventricular (LV)
myocardium have been proposed as targets for LV pacing during cardiac resynchronization …

Cardiac resynchronization therapy (CRT) is an effective procedure for patients with heart
failure but 30% of patients do not respond. This may be due to sub-optimal placement of the …

Introduction: Cardiac resynchronization therapy (CRT) is an effective pacemaker delivered
treatment for selected patients with heart failure with the target of restoring electro …

Background Myocardial scarring is associated with nonresponse to cardiac
resynchronization therapy (CRT) and conduction delay. Little is known about the …

Aim. To assess the effect of the size and pattern of myocardial structural injury, determined
by magnetic resonance imaging (MRI), on response to cardiac resynchronization therapy …

Background Up to 50% of patients do not respond to Cardiac Resynchronization Therapy
(CRT). Recent work has focused on quantifying mechanical dyssynchrony and left …

Myocardial scar is known to be associated with limited left ventricular (LV) reverse
remodeling after cardiac resynchronization therapy (CRT). However, the impact of diffuse …