Over the past few decades, significant advances in the care of patients with sickle cell
disease (SCD) have led to improvements in morbidity and survival. The average life span of …

In light of these observations, it is interesting to note that in our series the average age of
onset of symptoms referable to sickle cell disease was 40 months in patients under age 15 …

Seven of 21 patients with sickle cell anemia developed neurologic complications 5 to 243
days (median, 33 days) after allogeneic marrow transplantation. Among these 7 patients …

Sickle-cell anaemia is the most common cause of stroke in children, and stroke is one of the
most devastating complications of sickle-cell disease. Overt strokes are typically due to large …

Red cell transfusion has an important role in the management of sickle cell disease (SCD) in
both emergency and elective settings. However, because of insufficient randomised data, it …

Regular red cell transfusions are used in the management of numerous hematologic
disorders. In b-thalassemia major, red cell transfusions relieve the severe anemia, reduce …

Red cell transfusion remains a critical component of care for acute and chronic
complications of sickle cell disease. Randomized clinical trials demonstrated the benefits of …