Carcinogenicity of diallylnitrosamine following intragastric administration to Syrian hamsters

CJ Grandjean, J Althoff, PM Pour - Journal of the National …, 1985 - academic.oup.com
Single and multiple intragastric doses of diallylnitrosamine [(DAN) CAS: 16338-97-9]
administered to Syrian golden hamsters induced tumors, primarily of the respiratory tract, in …

Different responses to phenobarbital promotion in the development of γ-glutamyltranspeptidase-positive foci in the liver of rats initiated with diethylnitrosamine, N …

T SHIRAI, K IMAIDA, M OHSHIMA… - Japanese Journal of …, 1985 - jstage.jst.go.jp
The promoting activities of phenobarbital(PB) on the development of ƒÁ-glutamyl
transpeptidase-positive(ƒÁ-GT• ôUH• ô+• ôUS• ô) foci in rat liver with three different initiating …

Effect of phenobarbital, dichlorodiphenyltrichloroethane, and polychlorinated biphenyls on diethylnitrosamine-induced hepatocarcinogenesis

M NISHIZUMI - GANN Japanese Journal of Cancer Research, 1979 - jstage.jst.go.jp
Materials and Methods Two hundred male Wistar rats, 28 days old, were used.
Phenobarbital sodium, DDT, and PCB (Kanechlor 500) were used as tumor enhancers after …

Induction of tumours in rats by feeding nitrosatable amines together with sodium nitrite

W Lijinsky - Food and chemical toxicology, 1984 - Elsevier
Abstract Feed containing 0.2% allantoin or diphenhydramine (as the hydrochloride) or 0.1%
chlorpheniramine (as the maleate), with or without 0.2% sodium nitrite, was given ad lib. to …

Promotion mechanism of phenobarbital and partial hepatectomy in DENA hepatocarcinogenesis cell kinetics effect

H Barbason, C Rassenfosse, EH Betz - British journal of cancer, 1983 - nature.com
Abstract Diethylnitrosamine (DENA, 10 mg kg-1 per day) was fed to rats for 2, 4 and 6
weeks. One week after the cessation of DENA, animals were submitted either to partial …

Concordance of thresholds for carcinogenicity of N-nitrosodiethylamine

WJ Waddell, S Fukushima, GM Williams - Archives of toxicology, 2006 - Springer
Three publications on the carcinogenicity of N-nitrosodiethylamine (NDEA) in the livers of F-
344 or Wistar rats were examined for concordance of the data. Two reports recorded the …

Effect of phenobarbital on the development of liver tumors in juvenile and adult mice

MA Pereira, JE Klaunig, SLH Freund… - Journal of the National …, 1986 - academic.oup.com
The effect of long-term exposure to phenobarbital (CAS: 50-06-6) subsequent to tumor
initiation on the development of liver tumors in BALB/c and (C57BL/6× C3H/Anf) F1 …

Inhibitory effect of butylated hydroxyanisole and ethoxyquin on the induction of neoplastic lesions in rat liver after an initial treatment with N-ethyl-N …

N Ito, H TSUDA, T SAKATA, R HASEGAWA… - … Japanese Journal of …, 1983 - jstage.jst.go.jp
The effect of butylated hydroxyanisole(BHA) and ethoxyquin(EQ) on hepatocarcinogenesis
initiated with N-ethyl-N-hydroxyethylnitrosamine in rats was investigated. The results clearly …

Modulation by Indomethacin or Prostaglandin E2 of the Incidence of Diethylnitrosamine‐induced γ‐Glutamyltranspeptidase‐positive Foci in Rat Liver

G Taton, P Servais, P Galand - Japanese journal of cancer …, 1990 - Wiley Online Library
We investigated the effect of a pretreatment with indomethacin (IMC, ip 3.6 mg/kg body
weight (bw)) or dimethylprostaglandin E2 (PGE2, ip 10 μg/kg bw) on the incidence and …

Inhibition by cysteamine of hepatocarcinogenesis induced by N‐nitrosomorpholine in sprague‐dawley rats

M Tatsuta, H Iishi, M Baba - International journal of cancer, 1989 - Wiley Online Library
The effect of cysteamine (2‐aminoethanethiol hydrochloride) on hepatocarcinogenesis
induced by N‐nitrosomor‐pholine (NNM) was investigated in male Sprague‐Dawley rats …