The discovery of nerve growth factor (NGF) over 40 years ago led to the formulation of the
“Neurotrophic Factor Hypothesis”. This hypothesis states that developing neurons compete …

Summary mRNA coding for brain-derived neurotrophic factor (BDNF) has been detected in
cultured 1929 fibroblasts, rat dermal fibroblasts, and sciatic nerve Schwann cells, as well as …

A newly established, sensitive, two‐site enzyme‐immunoassay system for brain‐derived
neurotrophic factor (BDNF) is described. Using this system, we investigated the tissue …

Nerve growth factor promotes the survival of populations of sensory and sympathetic
neurons. Although ganglia have been used for classical assays of neurotrophin action …

Nerve growth factor (NGF) and brain‐derived neurotrophic factor (BDNF) are two members
of a family of neurotrophic factors which show both overlapping and distinct neurotrophic …

Human recombinant glial cell line‐derived neurotrophic factor (GDNF) was tested for its
ability to stimulate fiber formation and neuron survival in primary cultures of peripheral …

We used compartmented cultures to study the regulation of adult sensory neurite growth by
neurotrophins. We examined the effects of the neurotrophins nerve growth factor (NGF) …

We have used a pool of degenerate oligonucleotides representing all possible codons in
regions of homology between brain-derived neurotrophic factor (BDNF) and nerve growth …

The human nervous system is a vast network of several billion neu rons, or nerve cells,
endowed with the remarkable ability to receive, store and transmit information, In order to …

Brain‐derived neurotrophic factor (BDNF) is a member of a family of related neurotrophic
proteins which includes nerve growth factor (NGF) and hippocampus‐derived neurotrophic …