Initiating the immune response to invading pathogens, the innate immune system is
constituted of immune receptors (pattern recognition receptors, PRR) that sense microbe …

RIG-I-like receptors (RLRs) are cytosolic innate immune sensors that detect pathogenic RNA
and induce a systemic antiviral response. During the last decade, many studies focused on …

Retinoic acid-inducible gene I (RIG-I)-like receptors (RLRs) are key sensors of virus
infection, mediating the transcriptional induction of type I interferons and other genes that …

RIG-I is an essential innate immune receptor for detecting and responding to infection by
RNA viruses. RIG-I specifically recognizes the unique molecular features of viral RNA …

Mammalian cells have the ability to recognize virus infection and mount a powerful antiviral
response. Pattern recognition receptor proteins detect molecular signatures of virus infection …

Retinoic acid-inducible gene I (RIG-I)-like receptors (RLRs), which are pivotal sensors of
RNA virus invasions, mediate the transcriptional induction of genes encoding type I …

Viral and microbial pathogens contain specific motifs or pathogen-associated molecular
patterns (PAMPs) that are recognized by cell surface-and endosome-associated Toll-like …

Viral RNA is recognized by innate immune receptors from two different families. In
endolysosomal compartments, T oll‐like receptors (TLRs) 3, 7 and 8 recognize either double …

Pattern recognition receptors (PRRs) survey intra-and extracellular spaces for pathogen-
associated molecular patterns (PAMPs) within microbial products of infection. Recognition …

The RIG-I-like receptors (RLRs) RIG-I, MDA5, and LGP2 play a major role in pathogen
sensing of RNA virus infection to initiate and modulate antiviral immunity. The RLRs detect …