In silico genetic correlations of multidrug efflux pump gene expression in Staphylococcus aureus

C Kosmidis, CE DeMarco, E Frempong-Manso… - International journal of …, 2010 - Elsevier
Regulatory mechanisms for chromosomal genes encoding multidrug resistance (MDR)
efflux pumps (EPs) in Staphylococcus aureus are poorly defined. Microbiological …

Expression of multidrug resistance efflux pump genes in clinical and environmental isolates of Staphylococcus aureus

C Kosmidis, BD Schindler, PL Jacinto, D Patel… - International journal of …, 2012 - Elsevier
Increased expression of multidrug resistance efflux pump (MDR-EP) genes in clinical
isolates of Staphylococcus aureus occurs frequently, but its temporal and geographic …

Clonal relatedness is a predictor of spontaneous multidrug efflux pump gene overexpression in Staphylococcus aureus

BD Schindler, PL Jacinto, JAL Buensalido… - International journal of …, 2015 - Elsevier
Increased expression of genes encoding multidrug resistance efflux pumps (MDR-EPs)
contributes to antimicrobial agent and biocide resistance in Staphylococcus aureus …

Inability of a reserpine-based screen to identify strains overexpressing efflux pump genes in clinical isolates of Staphylococcus aureus

E Frempong-Manso, JL Raygada, CE DeMarco… - International journal of …, 2009 - Elsevier
Overexpression of efflux pump genes conferring multidrug resistance (MDR) in
Staphylococcus aureus results in reduced susceptibility to select biocides, dyes and …

Effect of substrate exposure and other growth condition manipulations on norA expression

GW Kaatz, SM Seo - Journal of Antimicrobial Chemotherapy, 2004 - academic.oup.com
Objectives: Multidrug efflux is a resistance mechanism that simultaneously affects
susceptibility to many structurally unrelated compounds. The regulation of norA expression …

Evaluation of multidrug efflux pump expression in clinical isolates of Staphylococcus. aureus

S Rajabi, A Shivaee, MA Khosravi, M Eshaghi… - Gene Reports, 2020 - Elsevier
Background One of the mechanisms of Staphylococcus aureus resistance to ciprofloxacin is
the presence of efflux pumps. The aim of this study was to determine the frequency and …

[HTML][HTML] Diversity of multidrug efflux genes and phenotypic evaluation of the in vitro resistance dynamics of clinical Staphylococcus aureus isolates using methicillin; a …

JF Antiabong, MM Kock, NM Mbelle… - The open microbiology …, 2017 - ncbi.nlm.nih.gov
Objectives: Methicillin-resistant Staphylococcus aureus (MRSA) across the world often leave
clinicians with little or no choice of treatment options. The multi-drug efflux (MDE) genes are …

[HTML][HTML] Analyses of multidrug efflux pump-like proteins encoded on the Staphylococcus aureus chromosome

BD Schindler, E Frempong-Manso… - Antimicrobial agents …, 2015 - Am Soc Microbiol
S. aureus possesses a large complement of genes encoding putative drug and toxin efflux
pumps, the majority of which reside on the chromosome and remain uncharacterized. The …

Multidrug efflux pump overexpression in Staphylococcus aureus after single and multiple in vitro exposures to biocides and dyes

AA Huet, JL Raygada, K Mendiratta, SM Seo… - …, 2008 - microbiologyresearch.org
Biocides and dyes are commonly employed in hospital and laboratory settings. Many of
these agents are substrates for multiple-drug resistance (MDR)-conferring efflux pumps of …

Epidemiology of efflux pumps genes mediating resistance among Staphylococcus aureus; A systematic review

S Hassanzadeh, MR Pourmand, R Mashhadi… - Microbial …, 2020 - Elsevier
Background Efflux of antibiotics is an effective resistance mechanism among antibiotic-
resistant Staphylococcus aureus. This systematic review aims to evaluate the frequency and …