It is now clearly established that the transfusion of blood from variant CJD (v-CJD) infected
individuals can transmit the disease. Since the number of asymptomatic infected donors …

Variant Creutzfeldt-Jakob disease (vCJD) is a human prion disease resulting from zoonotic
transmission of bovine spongiform encephalopathy (BSE). Documented cases of vCJD …

Variant CJD (vCJD) is an incurable, infectious human disease, likely arising from the
consumption of BSE-contaminated meat products. Whilst the epidemic appears to be …

Exposure of human populations to bovine spongiform encephalopathy through
contaminated food has resulted in< 250 cases of variant Creutzfeldt–Jakob disease (vCJD) …

BACKGROUND: It is not known whether variant CJD can be transmitted within the human
population by blood transfusion. The expression of normal cellular prion protein (PrPC) by …

Attempts to detect infectivity in the blood of humans and animals affected with transmissible
spongiform encephalopathies (TSEs or prion diseases) have often been inconclusive …

No transmission through transfusion has been reported for classic Creutzfeldt-Jakob
disease (CJD). Moreover, a series of epidemiological surveillance, case-control, and look …

Substantial evidence for prion transmission via blood transfusion exists for many
transmissible spongiform encephalopathy (TSE) diseases. Determining which cell …

The role of blood in the iatrogenic transmission of transmissible spongiform encephalopathy
(TSE) or prion disease has become an increasing concern since the reports of variant …

The host prion protein, PrPc, and its conformationally changed isoform, PrPsc, play an
essential role in the transmissible spongiform encephalopathy (TSE) infections. The prion …