Safety and immunogenicity of Chiron/Biocine® recombinant acellular pertussis-diphtheria-tetanus vaccine in infants and toddlers

SB Black, HR Shinefield, R Bergen, C Hart… - The Pediatric …, 1997 - journals.lww.com
Objective. To evaluate the safety and immunogenicity of the recombinant acellular
pertussisdiphtheria-tetanus (aPDT) vaccine (C-aPDT, Chiron/Biocine®). Study design. This …

Reactogenicity and immunogenicity of a three-component acellular pertussis vaccine administered as the primary series to 2, 4 and 6 month old infants in the United …

HH Bernstein, EP Rothstein, PP Associates… - Vaccine, 1995 - Elsevier
Five hundred and fifty-seven infants received either an acellular pertussis (DTaP) vaccine
containing pertussis toxoid (PT), filamentous hemagglutinin (FHA) and pertactin (PRN) or …

The 112-year odyssey of pertussis and pertussis vaccines—mistakes made and implications for the future

JD Cherry - Journal of the Pediatric Infectious Diseases Society, 2019 - academic.oup.com
Effective diphtheria, tetanus toxoids, whole-cell pertussis (DTwP) vaccines became
available in the 1930s, and they were put into routine use in the United States in the 1940s …

Reactogenicity and immunogenicity of reduced antigen content diphtheria–tetanus–acellular pertussis vaccines as a booster in 4–7-year-old children primed with …

R Dagan, K Igbaria, L Piglansky, F Van Brusteghem… - Vaccine, 1999 - Elsevier
Background. The recent introduction of acellular pertussis vaccines (Pa) offers the possibility
of booster doses in older children and adults. This can be conveniently accomplished by …

Duration of protection after first dose of acellular pertussis vaccine in infants

HE Quinn, TL Snelling, KK Macartney… - Pediatrics, 2014 - publications.aap.org
OBJECTIVE: Data on the effectiveness of the diphtheria–tetanus–acellular pertussis (DTaP)
vaccine in the first 4 years of life are sparse. We evaluated the vaccine effectiveness (VE) of …

Poor immune responses to a birth dose of diphtheria, tetanus, and acellular pertussis vaccine

NB Halasa, A O'Shea, JR Shi, BJ LaFleur… - The Journal of …, 2008 - Elsevier
OBJECTIVES: To evaluate the safety and immunogenicity of an additional birth dose of
diphtheria, tetanus, and acellular pertussis vaccine (DTaP). STUDY DESIGN: Fifty infants …

Association of reactions after consecutive acellular or whole-cell pertussis vaccine immunizations

MA Deloria, WC Blackwelder, MD Decker… - …, 1995 - publications.aap.org
Objective. To evaluate the relative frequency of adverse reactions after initial and
subsequent immunizations among infants receiving primary immunization with acellular …

Acellular pertussis vaccines for adolescents

ME Pichichero, JR Casey - The Pediatric infectious disease …, 2005 - journals.lww.com
Background: The epidemiology of pertussis is changing, with a clear increase in the number
of cases diagnosed in adolescents and adults. This development has spurred studies and …

Clinical experience of a tricomponent acellular pertussis vaccine combined with diphtheria and tetanus toxoids for primary vaccination in 22,505 infants

HJ Schmitt, A Schuind, M Knuf, K Beutel… - The Journal of …, 1996 - Elsevier
OBJECTIVES: To assess the safety and tolerability of 12 lots of SmithKline Beecham
Biologicals' diphtheria-tetanus-tricomponent acellular pertussis vaccine (DTaP) in a large …

Antibody response and reactions to completion of a four-dose series with a two-or three-component acellular pertussis vaccine compared to whole cell pertussis …

ME Pichichero, JL Green, AB Francis… - … journal of infectious …, 1996 - Taylor & Francis
We compared the reactions and immunogenicity of DT acellular pertussis (DTaP) vaccines
containing pertussis toxoid (PT) and filamentous haemagglutinin (FHA)(2-component DTaP) …