Coronary artery disease has a significant genetic predisposition, which mainly results from
atherosclerosis. Miniature pig is an excellent model to investigate atherosclerosis. This study …

Novel atherosclerotic lesions were induced in the Microminipig (MMP, registered with the
Japanese Ministry of Agriculture, Forestry and Fisheries as a novel variety of swine), the …

Type 2 diabetes is a major risk factor of the development of atherosclerosis in humans.
However, studies examining mechanisms underlying diabetes‐accelerated atherosclerosis …

抄録 G 隸 ttingen 系ミニブタ 24 頭を用い, 高脂肪・高コレステロール食群, 高脂肪食群および市販
のブタ用固型飼料給餌群の 3 群に分け, 給餌 1, 3, 6 および 9 ヵ月後に, 血清生化学的検査を行い …

To increase the incidence of coronary atherosclerosis in Watanabe heritable hyperlipidemic
(WHHL) rabbits, an animal model for familial hypercholesterolemia, selective breeding has …

Aim: Experimental studies of human atherogenesis require an appropriate animal model
that mimics human physiology and pathology. Because swine physiology is similar to …

In Western countries, lifestyle changes in the past century are considered to be a major
factor in obesity and related diseases such as atherosclerosis and diabetes. To gain a better …

Atherosclerotic lesions were observed in male and ovariectomized female Microminipig
(MMP) fed a high fat and cholesterol diet with sodium cholate (HFCD/SC) for 3 months …

A new animal model of atherosclerosis has been developed through genetic selection of
Japanese quail (Coturnix coturnix japonica) into susceptible (SUS) and resistant (RES) …

Background Animal models that mimic diet-induced human pathogenesis of chronic
diseases are of increasing importance in preclinical studies. The Ossabaw pig is an …