Polymer nanoparticle–protein interface. Evaluation of the contribution of positively charged functional groups to protein affinity

Y Yonamine, K Yoshimatsu, SH Lee… - … applied materials & …, 2013 - ACS Publications
Cationic-functionalized polymer nanoparticles (NPs) show strikingly distinct affinities to
proteins depending on the nature of the cationic functional group. N-Isopropylacrylamide …

ELISA-mimic screen for synthetic polymer nanoparticles with high affinity to target proteins

Y Yonamine, Y Hoshino, KJ Shea - Biomacromolecules, 2012 - ACS Publications
Synthetic polymer nanoparticles (NPs) that display high affinity to protein targets have
significant potential for medical and biotechnological applications as protein capture agents …

Molecular interactions of different size AuNP–COOH nanoparticles with human fibrinogen

J Deng, M Sun, J Zhu, C Gao - Nanoscale, 2013 - pubs.rsc.org
Protein adsorption influences greatly the performance of materials used in biotechnology
and biomedicine. The binding of fibrinogen (Fg) to nanoparticles (NPs) can result in protein …

[HTML][HTML] Protein-Nanoparticle Interactions Govern the Interfacial Behavior of Polymeric Nanogels: Study of Protein Corona Formation at the Air/Water Interface

F Traldi, P Liu, I Albino, L Ferreira, A Zarbakhsh… - International Journal of …, 2023 - mdpi.com
Biomedical applications of nanoparticles require a fundamental understanding of their
interactions and behavior with biological interfaces. Protein corona formation can alter the …

[HTML][HTML] Interaction between synthetic particles and biomacromolecules: fundamental study of nonspecific interaction and design of nanoparticles that recognize target …

Y Hoshino, H Lee, Y Miura - Polymer Journal, 2014 - nature.com
This article provides a brief review of the literature on the interaction between synthetic
particles and biomacromolecules. Understanding the nonspecific interactions between …

Surface functionalization of nanoparticles with polyethylene glycol: effects on protein adsorption and cellular uptake

B Pelaz, P del Pino, P Maffre, R Hartmann, M Gallego… - ACS …, 2015 - ACS Publications
Here we have investigated the effect of enshrouding polymer-coated nanoparticles (NPs)
with polyethylene glycol (PEG) on the adsorption of proteins and uptake by cultured cells …

Engineering the Bio–Nano Interface Using a Multifunctional Coordinating Polymer Coating

W Wang, H Mattoussi - Accounts of Chemical Research, 2020 - ACS Publications
Conspectus In the past three decades, interest in using nanoparticles as diagnostic tools to
interrogate various biosystems has witnessed remarkable growth. For instance, it has been …

Ionic strength-responsive binding between nanoparticles and proteins

X Wang, S Zhang, Y Xu, X Zhao, X Guo - Langmuir, 2018 - ACS Publications
Electrostatic interaction is a strong, dominant nonspecific interaction which was extensively
studied in protein–nanoparticle (NP) interactions [Lounis, FM; J. Phys. Chem. B 2017, 121 …

Synthesis and characterization of peptide-functionalized polymeric nanoparticles

S Taylor, L Qu, A Kitaygorodskiy, J Teske… - …, 2004 - ACS Publications
There have been many studies of polymeric nanoparticles as carriers for biomolecules such
as proteins and peptides. Among widely discussed applications are targeted drug delivery …

Synthetic polymer nanoparticle–polysaccharide interactions: A systematic study

Z Zeng, J Patel, SH Lee, M McCallum… - Journal of the …, 2012 - ACS Publications
The interaction between synthetic polymer nanoparticles (NPs) and biomacromolecules (eg,
proteins, lipids, and polysaccharides) can profoundly influence the NPs fate and function …