Why are dendritic cells important in allergic diseases of the respiratory tract?

JW Upham, PA Stumbles - Pharmacology & therapeutics, 2003 - Elsevier
Increasing evidence points to the role of antigen-presenting dendritic cells (DC) in regulating
adaptive immune responses. DC are especially sensitive to signals derived from microbes …

The role of dendritic cells in immune regulation and allergic airway inflammation

JW Upham - Respirology, 2003 - Wiley Online Library
Dendritic cells (DC) are potent antigen presenting cells that display an extraordinary
capacity to present antigen to naïve T‐cells and initiate primary immune responses. In the …

Dendritic cells in asthma: a function beyond sensitization

LS Van Rijt, BN Lambrecht - Clinical & Experimental Allergy, 2005 - Wiley Online Library
Allergic asthma is one of the most common chronic diseases in western society,
characterized by variable airway obstruction, mucus hypersecretion and infiltration of the …

Human dendritic cells in allergic asthma and rhinitis

A Froidure, C Pilette - Medecine Sciences: M/S, 2015 - europepmc.org
The role of dendritic cells (DC) in the pathogenesis of allergic asthma and rhinitis has been
highlighted for 15 years. In this review, we summarize key findings concerning DC function …

Dendritic cells revisited in human allergic rhinitis and asthma

A Froidure, C Shen, C Pilette - Allergy, 2016 - Wiley Online Library
The role of dendritic cells (DC s) in airway allergy has been studied for 15 years; recent data
has highlighted the cross talk with airway epithelial cells and environmental factors …

Recent progress in the biology of airway dendritic cells and implications for understanding the regulation of asthmatic inflammation

H Hammad, BN Lambrecht - Journal of allergy and clinical immunology, 2006 - Elsevier
Dendritic cells (DCs) are crucial in determining the outcome of antigen encounter and
integrating signals derived from the antigen, its inflammatory context, and the host …

The role of dendritic cells in asthma

MA Gill - Journal of Allergy and Clinical Immunology, 2012 - Elsevier
Dendritic cells (DCs) are known to play a central role in sensing the presence of foreign
antigens and infectious agents and in initiating appropriate immune responses. More …

Dendritic cells in asthma

MJ van Helden, BN Lambrecht - Current opinion in immunology, 2013 - Elsevier
Highlights•Dendritic cells (DCs) are essential for inducing Th2 immunity to several
allergens.•Similar to other organs, lung DCs are a heterogeneous population of …

The role of dendritic cells in asthma

PG Holt, JW Upham - Current opinion in allergy and clinical …, 2004 - journals.lww.com
The role of dendritic cells in asthma : Current Opinion in Allergy and Clinical Immunology The
role of dendritic cells in asthma : Current Opinion in Allergy and Clinical Immunology Log in or …

Dendritic cells and epithelial cells: linking innate and adaptive immunity in asthma

H Hammad, BN Lambrecht - Nature Reviews Immunology, 2008 - nature.com
Dendritic cells (DCs) are generally held responsible for initiating and maintaining allergic T
helper 2 (TH2)-cell responses to inhaled allergens in asthma. Although the epithelium was …