Mechanisms for modulation of neural plasticity and axon regeneration by chondroitin sulphate

S Miyata, H Kitagawa - The journal of biochemistry, 2015 - academic.oup.com
Chondroitin sulphate proteoglycans (CSPGs), consisting of core proteins linked to one or
more chondroitin sulphate (CS) chains, are major extracellular matrix (ECM) components of …

Chondroitin sulphate proteoglycans: key modulators of spinal cord and brain plasticity

K Bartus, ND James, KD Bosch, EJ Bradbury - Experimental neurology, 2012 - Elsevier
Chondroitin sulphate proteoglycans (CSPGs) are a family of inhibitory extracellular matrix
molecules that are highly expressed during development, where they are involved in …

Chondroitin sulfate proteoglycans: key modulators in the developing and pathologic central nervous system

SM Dyck, S Karimi-Abdolrezaee - Experimental neurology, 2015 - Elsevier
Abstract Chondroitin Sulfate Proteoglycans (CSPGs) are a major component of the
extracellular matrix in the central nervous system (CNS) and play critical role in the …

Chondroitin sulfate proteoglycans: key modulators of neuronal plasticity, long-term memory, neurodegenerative, and psychiatric disorders

X Yang - Reviews in the Neurosciences, 2020 - degruyter.com
The chondroitin sulfate proteoglycans (CSPGs) are large groups of heterogenous
proteoglycans that are mainly expressed by reactive astrocytes in the central nervous …

Targeting the neural extracellular matrix in neurological disorders

S Soleman, MA Filippov, A Dityatev, JW Fawcett - Neuroscience, 2013 - Elsevier
The extracellular matrix (ECM) is known to regulate important processes in neuronal cell
development, activity and growth. It is associated with the structural stabilization of neuronal …

Proteoglycans in the central nervous system: plasticity, regeneration and their stimulation with chondroitinase ABC

JCF Kwok, F Afshari, G Garcia-Alias… - Restorative neurology …, 2008 - content.iospress.com
After injury to the mammalian central nervous system (CNS), neurons are not able to
regenerate their axons and recovery is limited by restricted plasticity. Axon regeneration is …

Sugar-dependent modulation of neuronal development, regeneration, and plasticity by chondroitin sulfate proteoglycans

GM Miller, LC Hsieh-Wilson - Experimental neurology, 2015 - Elsevier
Chondroitin sulfate proteoglycans (CSPGs) play important roles in the developing and
mature nervous system, where they guide axons, maintain stable connections, restrict …

The role of chondroitin sulfate proteoglycans in regeneration and plasticity in the central nervous system

CM Galtrey, JW Fawcett - Brain research reviews, 2007 - Elsevier
Chondroitin sulfate proteoglycans (CSPGs) consist of a core protein and glycosaminoglycan
(GAG) chains. There is enormous structural diversity among CSPGs due to variation in the …

Chondroitin sulfate proteoglycans in the nervous system: inhibitors to repair

JR Siebert, A Conta Steencken… - BioMed research …, 2014 - Wiley Online Library
Chondroitin sulfate proteoglycans (CSPGs) are widely expressed in the normal central
nervous system, serving as guidance cues during development and modulating synaptic …

Chondroitin sulfate proteoglycans in neural development and regeneration

T Laabs, D Carulli, HM Geller, JW Fawcett - Current opinion in …, 2005 - Elsevier
Proteoglycans are of two main types, chondroitin sulfate (CSPGs) and heparin sulfate
(HSPGs). The CSPGs act mainly as barrier-forming molecules, whereas the HSPGs stabilise …