Some semen characteristics of eight male patients with clinically inactive ulcerative colitis
were investigated. Semen analysis was carried out twice during sali-cylazosulfapyridine …

Seminal abnormalities are commonly found during sulphasalazine treatment. Although
these changes appear reversible after drug withdrawal this may result in colitis relapse …

Mesalazine is a well-established treatment for ulcerative colitis. A young man treated with
mesalazine for proctitis was found to have pathological semen with a count of only 3× 106 …

Our purpose was to study the effects of long‐term salazopyrine treatment on male fertility.
Seven patients, 21–37 years old, who had been treated for ulcerative colitis with 3 g/day of …

Seminal abnormalities are a common side effect of Salazosulphapyridine (SASP) treatment.
We evaluated semen qualities and sex hormone concentrations in 11 patients with …

Recently, several reports have suggested that salicylazosulfapyridine causes a reduction in
semen quality in patients with ulcerative colitis. After withdrawal of the drug pregnancies …

The semen of 11 patients with inflammatory bowel disease treated with sulphasalazine
(Salazopyrin) was analysed and compared with that of 6 men with similar disease not …

Sulfasalazine, a drug used in the treatment of inflammatory bowel disease, has been
associated with male infertility, an effect attributed to sulfapyridine rather than to 5 …

Background. Use of sulphasalazine in ulcerative colitis patients is hampered by a variety of
side-effects, including male infertility. 5-aminosalicylic acid is better tolerated and has been …

Rijk MCM, van Schaik A, van Tongeren JHM. Disposition of mesalazine from mesalazine-
delivering drugs in patients with inflammatory bowel disease, with and without diarrhoea …