Angiogenesis is crucial in the progression of a number of pathological conditions, such as
diabetic retinopathy, rheumatoid arthritis, psoriasis, and cancer [1]. In contrast to vessels in …

Ample interest has been evoked in using placental angiogenesis as a target for the
development of diagnosis tools and potential therapeutics for pregnancy complications …

Fra1 is an immediate-early gene encoding a member of the AP-1 transcription factor family,
which has diverse roles in development and oncogenesis. To determine the function of Fra1 …

The importance of the placenta and its vascular development to fetal growth and
development has been appreciated since ancient times. Based on numerous studies in …

Abnormal placentation is considered as an underlying cause of various pregnancy
complications such as miscarriage, preeclampsia and intrauterine growth restriction, the …

Mammalian embryos have an intimate relationship with their mothers, particularly with the
placental vasculature from which embryos obtain nutrients essential for growth. It is an …

Successful implantation and placentation requires that extravillous cytotrophoblast acquires
an endovascular phenotype and remodels uterine spiral arteries. Defects in this mechanism …

Expression of placental growth factor (PGF) is closely associated with placental perfusion in
early pregnancy. PGF is primarily expressed in placental trophoblasts, and its expression …

The early blood vessels of the embryo and yolk sac in mammals develop by aggregation of
de novo–forming angioblasts into a primitive vascular plexus, which then undergoes a …

Blood and endothelium arise in close association during development, possibly from a
common precursor, the hemangioblast [1–4]. Genes essential for blood and endothelial …