Antiviral treatment of cytomegalovirus infection and resistant strains

A Schreiber, G Härter, A Schubert… - Expert opinion on …, 2009 - Taylor & Francis
This review discusses the management of resistant cytomegalovirus and prevention
strategies for fatal therapy failures. Five drugs, ganciclovir/valganciclovir, cidofovir, foscarnet …

Antiviral treatment of cytomegalovirus infection: an update

G Härter, D Michel - Expert opinion on pharmacotherapy, 2012 - Taylor & Francis
This editorial summarizes recent developments in the management of ganciclovir-resistant
human cytomegalovirus (HCMV) infections. All current drugs available for systemic …

Antiviral drug resistance of human cytomegalovirus

NS Lurain, S Chou - Clinical microbiology reviews, 2010 - Am Soc Microbiol
The study of human cytomegalovirus (HCMV) antiviral drug resistance has enhanced
knowledge of the virological targets and the mechanisms of antiviral activity. The currently …

In vitro evaluation of current and novel antivirals in combination against human cytomegalovirus

MS O'Brien, KC Markovich, D Selleseth, AV DeVita… - Antiviral research, 2018 - Elsevier
Human cytomegalovirus (HCMV) can cause severe disease in patients with compromised or
immature immune systems. Currently approved pharmacotherapies for the treatment of …

Resistance of human cytomegalovirus to antiviral drugs

A Erice - Clinical Microbiology Reviews, 1999 - Am Soc Microbiol
Resistance of cytomegalovirus (CMV) to antiviral agents is a well-recognized phenomenon
that has been observed in the laboratory and in the clinical setting. Infections caused by …

New inhibitors of human cytomegalovirus (HCMV) on the horizon

E De Clercq - Journal of Antimicrobial Chemotherapy, 2003 - academic.oup.com
There are at present five compounds that have been officially licensed for the treatment of
human cytomegalovirus (HCMV) infections: ganciclovir [GCV, 9-(1, 3-dihydroxy-2 …

[HTML][HTML] Challenges, recent advances and perspectives in the treatment of human cytomegalovirus infections

SJ Chen, SC Wang, YC Chen - Tropical Medicine and Infectious Disease, 2022 - mdpi.com
Human cytomegalovirus (HCMV) is ubiquitous worldwide and elicits global health problems.
The diseases associated with HCMV are a serious threat to humans, especially for the sick …

Antiviral treatment of cytomegalovirus infection

A Ahmed - Infectious Disorders-Drug Targets (Formerly Current …, 2011 - ingentaconnect.com
Cytomegalovirus (CMV) is an opportunistic pathogen associated with significant morbidity
and mortality in immunocompromised hosts. Antiviral agents specifically targeting CMV were …

The search for new therapies for human cytomegalovirus infections

MN Prichard, ER Kern - Virus research, 2011 - Elsevier
Ganciclovir (GCV), the therapy of choice for human cytomegalovirus (CMV) infections and
foscarnet, a drug used to treat GCV-resistant CMV infections was approved more than …

Update in management of ganciclovir-resistant cytomegalovirus infection

RK Avery - Current opinion in infectious diseases, 2008 - journals.lww.com
Antiviral-resistant cytomegalovirus infection remains a feared complication of transplantation
but is less frequently seen in AIDS patients in the current era. New research on resistance …