[HTML][HTML] Molecular basis of receptor binding and antibody neutralization of Omicron

Q Hong, W Han, J Li, S Xu, Y Wang, C Xu, Z Li, Y Wang… - Nature, 2022 - nature.com
Abstract The SARS-CoV-2 Omicron variant exhibits striking immune evasion and is
spreading rapidly worldwide. Understanding the structural basis of the high transmissibility …

Cryo-EM structure of a SARS-CoV-2 omicron spike protein ectodomain

G Ye, B Liu, F Li - Nature communications, 2022 - nature.com
The omicron variant of SARS-CoV-2 has been spreading rapidly across the globe. The virus-
surface spike protein plays a critical role in the cell entry and immune evasion of SARS-CoV …

[PDF][PDF] Structures of Omicron spike complexes and implications for neutralizing antibody development

H Guo, Y Gao, T Li, T Li, Y Lu, L Zheng, Y Liu, T Yang… - Cell reports, 2022 - cell.com
The emergence of the SARS-CoV-2 Omicron variant is dominant in many countries
worldwide. The high number of spike mutations is responsible for the broad immune evasion …

[HTML][HTML] Omicron Spike protein has a positive electrostatic surface that promotes ACE2 recognition and antibody escape

HH Gan, J Zinno, F Piano, KC Gunsalus - Frontiers in Virology, 2022 - frontiersin.org
High transmissibility is a hallmark of the Omicron variant of SARS-CoV-2. Understanding the
molecular determinants of Omicron's transmissibility will impact development of intervention …

Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies

Y Cao, J Wang, F Jian, T Xiao, W Song, A Yisimayi… - Nature, 2022 - nature.com
Abstract The SARS-CoV-2 B. 1.1. 529 (Omicron) variant contains 15 mutations of the
receptor-binding domain (RBD). How Omicron evades RBD-targeted neutralizing antibodies …

[HTML][HTML] Neutralization and stability of SARS-CoV-2 Omicron variant

C Zeng, JP Evans, P Qu, J Faraone, YM Zheng… - biorxiv, 2021 - ncbi.nlm.nih.gov
Abstract The SARS-CoV-2 B. 1.1. 529/Omicron variant was first characterized in South Africa
and was swiftly designated a variant of concern 1. Of great concern is its high number of …

Boosting immunity to Omicron

X Shen - Nature Medicine, 2022 - nature.com
Boosting immunity to Omicron | Nature Medicine Skip to main content Thank you for visiting
nature.com. You are using a browser version with limited support for CSS. To obtain the best …

Sars-cov-2 omicron variant: Ace2 binding, cryo-em structure of spike protein-ace2 complex and antibody evasion

D Mannar, JW Saville, X Zhu, SS Srivastava… - BioRxiv, 2021 - biorxiv.org
The newly reported Omicron variant is poised to replace Delta as the most rapidly spread
SARS-CoV-2 variant across the world. Cryo-EM structural analysis of the Omicron variant …

Structural analysis of the Spike of the Omicron SARS-COV-2 variant by cryo-EM and implications for immune evasion

D Ni, K Lau, P Turelli, C Raclot, B Beckert, S Nazarov… - BioRxiv, 2021 - biorxiv.org
ABSTRACT The Omicron (B. 1.1. 529) SARS-COV-2 was reported on November 24, 2021
and declared a variant of concern a couple of days later., With its constellation of mutations …

[PDF][PDF] Structural and functional characterizations of infectivity and immune evasion of SARS-CoV-2 Omicron

Z Cui, P Liu, N Wang, L Wang, K Fan, Q Zhu, K Wang… - Cell, 2022 - cell.com
Summary The SARS-CoV-2 Omicron variant with increased fitness is spreading rapidly
worldwide. Analysis of cryo-EM structures of the spike (S) from Omicron reveals amino acid …