Reduced spinal cord sensitization to C‐fibre stimulation in mice over‐expressing galanin
S Grass, JN Crawley, XJ Xu… - European Journal of …, 2003 - Wiley Online Library
The neuropeptide galanin may have a role in spinal nociception. In this study, we examined
the excitability of the flexor reflex and its sensitization by repetitive stimulation of nociceptive …
the excitability of the flexor reflex and its sensitization by repetitive stimulation of nociceptive …
Effects of galanin on wide-dynamic range neuron activity in the spinal dorsal horn of rats with sciatic nerve ligation
SL Xu, YP Zhang, T Lundeberg, LC Yu - Regulatory peptides, 2000 - Elsevier
Galanin is a 29-amino acid peptide with a suggested role in nociception. The effect of
galanin on wide-dynamic range neuron discharge frequency in rats with nerve ligation, used …
galanin on wide-dynamic range neuron discharge frequency in rats with nerve ligation, used …
Central and peripheral expression of galanin in response to inflammation
RR Ji, X Zhang, Q Zhang, Å Dagerlind, S Nilsson… - Neuroscience, 1995 - Elsevier
Using in situ hybridization, immunohistochemistry and receptor binding methodology, the
galanin messenger RNA levels, galanin binding and galanin-like immunoreactivity were …
galanin messenger RNA levels, galanin binding and galanin-like immunoreactivity were …
Galanin-mediated control of pain: enhanced role after nerve injury.
Z Wiesenfeld-Hallin, XJ Xu, U Langel… - Proceedings of the …, 1992 - National Acad Sciences
The endogenous inhibitory role of the neuropeptide galanin in pain transmission and spinal
cord excitability was demonstrated by the use of a high-affinity galanin receptor antagonist …
cord excitability was demonstrated by the use of a high-affinity galanin receptor antagonist …
Galanin expression in adult human dorsal root ganglion neurons: initial observations
Human dorsal root ganglia (DRGs) were obtained during various procedures and processed
for single and double in situ hybridisation using oligonucleotide probes complementary to …
for single and double in situ hybridisation using oligonucleotide probes complementary to …
Generation and phenotypic characterization of a galanin overexpressing mouse
K Holmberg, E Kuteeva, P Brumovsky, U Kahl… - Neuroscience, 2005 - Elsevier
In most parts of the peripheral nervous system galanin is expressed at very low levels. To
further understand the functional role of galanin, a mouse overexpressing galanin under the …
further understand the functional role of galanin, a mouse overexpressing galanin under the …
[HTML][HTML] Cloning and expressional characterization of a novel galanin receptor: identification of different pharmacophores within galanin for the three galanin receptor …
S Wang, C He, T Hashemi, M Bayne - Journal of Biological Chemistry, 1997 - ASBMB
Galanin, a 29–30 amino acid neuropeptide, is found in the central and peripheral nervous
systems and displays several important physiological activities. The actions are believed to …
systems and displays several important physiological activities. The actions are believed to …
Galaninergic mechanisms at the spinal level: focus on histochemical phenotyping
The 29/30 aminoacid neuropeptide galanin is present in a small population of DRG neurons
under normal condition but is strongly upregulated after nerve injury. There is evidence that …
under normal condition but is strongly upregulated after nerve injury. There is evidence that …
Distribution of galanin-1,-2 and-3 receptor messenger RNAs in central and peripheral rat tissues
SM Waters, JE Krause - Neuroscience, 1999 - Elsevier
Galanin is a neuropeptide widely expressed in the central nervous system and periphery. In
rat, three galanin-binding receptors have been cloned and characterized. We report the …
rat, three galanin-binding receptors have been cloned and characterized. We report the …
New high affinity peptide antagonists to the spinal galanin receptor
XJ Xu, Z Wiesenfeld‐Hallin, Ü Langel… - British journal of …, 1995 - Wiley Online Library
1 The role of endogenous galanin in somatosensory processing has been studied with
galanin receptor antagonists. The new galanin receptor ligands C7, M32, M38 and M40 bind …
galanin receptor antagonists. The new galanin receptor ligands C7, M32, M38 and M40 bind …