An exaggerated interstitial and perivascular deposition of fibrillar collagen has been
demonstrated in myocardial hypertrophy due to hypertension. 3 Mechanical stress forces …

Organs are composed of highly differentiated, very specialized parenchymal cells
surrounded by stroma consisting of extracellular matrix, tissue fluid, and undifferentiated …

The cardiac interstitium is composed of nonmyocyte cells and a structural protein network
which plays a dominant role in governing the structure, architecture, and mechanical …

Myocardial fibrosis is one of the histologic constituents of myocardial remodeling present in
hypertensive patients with hypertensive heart disease. In fact, an exaggerated interstitial and …

Colocalization of myocardial fibrosis and inflammatory cells in rats. - Abstract - Europe PMC
Sign in | Create an account https://orcid.org Europe PMC Menu About Tools Developers Help …

Patterns of myocardial fibrosis in idiopathic cardiomyopathies and chronic Chagasic
cardiopathy. - Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe …

Fibrosis is a fundamental component of the adverse structural remodeling of myocardium
present in the failing heart. Replacement fibrosis appears at sites of previous cardiomyocyte …

Elevations in myocardial stress initiate structural remodeling of the heart in an attempt to
normalize the imposed stress. This remodeling consists of cardiomyocyte hypertrophy and …

There is a complex collagen network in the heart. Various components have been identified
and generally on the basis of form and position some functions have been ascribed to one …

There is an extensive collagen network in the heart. The precise anatomy and function of
this system has not been fully elucidated. The system does appear to contribute to diastolic …