Purpose Polymeric micelles are attractive nanocarriers for tumor-targeted delivery of
paclitaxel (PTX). High antitumor efficacy and low toxicity require that PTX mainly …

Background/Aim: Polymeric micelles are promising vehicles for paclitaxel delivery. Further
improvement in the stability of the micelle formulation is desirable. Materials and Methods …

High tumor targeting and sustained drug concentration are key points for successful anti-
tumor therapy, however, it is a challenging task. In this work, a novel micelle formulation of …

Abstract Paclitaxel (PTX), especially albumin-bound PTX in clinical, has displayed
significant inhibition of tumor growth in patients. But the systemic distribution and poor water …

In this study a novel receptor-targeted micelle delivery system based on tocopherol
succinate-chitosan-polyethylene glycol-folic acid (TS-CS-PEG-FA) was synthesized and …

Nanoscale polymeric micelles have promising applications as drug delivery systems (DDS).
In this work, to improve the anti-tumor activity and eliminate toxicity of the commercial …

A water-insoluble anti-tumor agent, paclitaxel (PTX) was successfully incorporated into
novel-targeted polymeric micelles based on tocopherol succinate-chitosan-polyethylene …

D-α-Tocopheryl polyethylene glycol 1000 succinate (TPGS)-modified carboxymethyl
chitosan-rhein (TCR) polymeric micelles (PMs) self-assembled by TCR conjugate were …

Mucopermeating nanocargoes being able to overcome mucosal, as well as extracellular
barrier leads to enhance penetration of poorly soluble anticancer drugs at its target site. We …

In order to decrease the toxicity of paclitaxel (PTX) and increase the efficiency, we
developed an amphiphilic PTX injection system using a biodegradable and biocompatible …