A novel micelle formulation of paclitaxel (PTX) has been prepared for the purpose of
prolonging the blood circulation time as well as modifying the biodistribution of PTX in …

Although doxorubicin (DOX) and paclitaxel (PTX) are widely used in clinic as
chemotherapeutics, both drug substances are found to be glycoprotein P (P-gp) substrates …

Drug loading is a key procedure in the preparation of drug-loaded nano-carriers. In this
study, the paclitaxel (PTX)-loaded polymeric complex micelles (FA-P123-PTX/PTX micelles) …

Tumor-targeting micelles for the delivery of paclitaxel (PTX) were developed based on folic
acid and α-tocopherol succinate conjugated hyaluronic acid (FA-HA-TOS). The conjugate …

Development of successful formulations for poorly water-soluble drugs remains a
longstanding critical and challenging issue in cancer therapy. As a potential drug carrier of …

In the present study, polymeric micelles constituted of N-(2-hydroxypropyl) methacrylamide
(HPMA) and methoxypoly (ethylene glycol)(mPEG)-based copolymer, mPEG-b-HPMA was …

The aim of this study was to develop chitosan derivative polymeric micelles for co-delivery of
paclitaxel (PTX) and α-tocopherol succinate (α-TS) to the cancer cells to improve the …

Purpose The purpose of the study was to devise and evaluate crosslinked nanoassemblies
to achieve enhanced drug delivery to tumors. Methods A novel copolymer comprised of …

The novel self-assembling bottlebrush polyethylene glycol-polynorbornene-thiocresol block
copolymers (PEG-PNB-TC) were synthesized by the ring opening metathesis polymerization …

Abstract Fenretinide (4-HPR), as a semi-synthetic retinoid, has apoptosis-promoting effects
as a single agent and chemotherapy synergist in vitro. When a human ovarian cancer cells …