We have previously improved the bioactivity of PEG5k-FTS2 system by incorporating
disulfide bond (PEG5k-SS-FTS2) to facilitate the release of farnesyl thiosalicylic acid (FTS) …

In this study, new amphiphilic block copolymers, methoxypoly (ethylene glycol)-b-poly (ε-
caprolactone-co-l-lactide)[MPEG-P (CL-co-LLA)] copolymers were designed and …

Folate has been used as a targeting moiety of various anticancer agents to increase their
cellular uptake within target cells since folate receptors (FR) are vastly overexpressed in …

In present study, two types of micelles based on sodium cholate (NaC) were prepared
through non-covalent bonding interaction and the potential of micelles as oral drug delivery …

Poly (ethylene glycol)-block-poly (aspartate-hydrazide)(PEG-p (Asp-Hyd)) was modified
using either levulinic acid (LEV) or 4-acetyl benzoic acid (4AB) attached via hydrazone …

Micelles are promising a nano drug carrier for cancer therapy. However, their application is
often limited due to the instability of them in vivo. Herein, we reported the development of …

A polymer micelle-based drug delivery system has faced many challenges due to the lack of
stability especially after being diluted in blood, resulting in a premature release. Herein, we …

To avoid poly (ethylene glycol)-related issues of nanomedicines such as accelerated blood
clearance, fully N-2-hydroxypropyl methacrylamide (HPMAm)-based polymeric micelles …

Biodegradable micelles were prepared from poly (ε-caprolactone)-g-poly (2-hydroxyethyl
methacrylate)(PCL-g-PHEMA) graft copolymers and investigated for controlled release of …

To reduce the side effects and drug resistance in cancer chemotherapy, we have examined
the in vitro efficacy of the combination of paclitaxel (PTX) and doxorubicin (DOX) loaded in …