Pulmonary arterial hypertension (PAH) is a severe cardiopulmonary dysfunctional disease,
characterized by progressive vascular remodeling. Inflammation is an increasingly …

Inflammation is important for the initiation and the maintenance of vascular remodeling in
most of the animal models of pulmonary arterial hypertension (PAH), and therapeutic …

Pulmonary arterial hypertension (PAH) pathobiology involves a remodeling process in distal
pulmonary arteries, as well as vasoconstriction and in situ thrombosis, leading to enhanced …

Abstract According to the World Symposium Pulmonary Hypertension (WSPH) classification,
pulmonary hypertension (PH) is classified into five categories based on etiology. Among …

Pulmonary arterial hypertension is characterized by a remodeling of pulmonary arteries with
endothelial cell, fibroblast, and vascular smooth muscle cell activation and proliferation …

Physicians treating patients with pulmonary vascular diseases must account for a wide
spectrum of etiologies and presentations that are associated with the syndrome, including …

Perivascular inflammation is a prominent pathologic feature in most animal models of
pulmonary hypertension (PH) as well as in pulmonary arterial hypertension (PAH) patients …

Pulmonary arterial hypertension (PAH) is a relatively rare disease, but, today, its incidence
tends to increase. The severe course of the disease and poor patient survival rate make …

Altered immunity and inflammation are increasingly recognized features of pulmonary
arterial hypertension (PAH). This is suggested by infiltration of various inflammatory cells …

Introduction: Inflammatory cells are present in the lungs from patients with many, if not all,
forms of severe pulmonary hypertension. Areas covered: Historically the first inflammatory …