[HTML][HTML] Intervention with citrus flavonoids reverses obesity and improves metabolic syndrome and atherosclerosis in obese Ldlr−/− mice
AC Burke, BG Sutherland, DE Telford… - Journal of Lipid …, 2018 - ASBMB
Obesity and its associated metabolic dysfunction and cardiovascular disease risk represent
a leading cause of adult morbidity worldwide. Currently available pharmacological therapies …
a leading cause of adult morbidity worldwide. Currently available pharmacological therapies …
Preventive and ameliorating effects of citrus D-limonene on dyslipidemia and hyperglycemia in mice with high-fat diet-induced obesity
L Jing, Y Zhang, S Fan, M Gu, Y Guan, X Lu… - European journal of …, 2013 - Elsevier
Abstract d-limonene is a major constituent in citrus essential oil, which is used in various
foods as a flavoring agent. Recently, d-limonene has been reported to alleviate fatty liver …
foods as a flavoring agent. Recently, d-limonene has been reported to alleviate fatty liver …
Citrus flavonoids as regulators of lipoprotein metabolism and atherosclerosis
Citrus flavonoids are polyphenolic compounds with significant biological properties. This
review summarizes recent advances in understanding the ability of citrus flavonoids to …
review summarizes recent advances in understanding the ability of citrus flavonoids to …
[HTML][HTML] Naringenin prevents cholesterol-induced systemic inflammation, metabolic dysregulation, and atherosclerosis in Ldlr−/− mice [S]
JM Assini, EE Mulvihill, BG Sutherland, DE Telford… - Journal of lipid …, 2013 - ASBMB
Obesity-associated chronic inflammation contributes to metabolic dysfunction and
propagates atherosclerosis. Recent evidence suggests that increased dietary cholesterol …
propagates atherosclerosis. Recent evidence suggests that increased dietary cholesterol …
Naringenin decreases progression of atherosclerosis by improving dyslipidemia in high-fat–fed low-density lipoprotein receptor–null mice
EE Mulvihill, JM Assini, BG Sutherland… - … , and vascular biology, 2010 - Am Heart Assoc
Objective—Naringenin is a citrus flavonoid that potently inhibits the assembly and secretion
of apolipoprotein B100–containing lipoproteins in cultured hepatocytes and improves the …
of apolipoprotein B100–containing lipoproteins in cultured hepatocytes and improves the …
Naringenin prevents dyslipidemia, apolipoprotein B overproduction, and hyperinsulinemia in LDL receptor–null mice with diet-induced insulin resistance
EE Mulvihill, EM Allister, BG Sutherland, DE Telford… - Diabetes, 2009 - Am Diabetes Assoc
OBJECTIVE The global epidemic of metabolic syndrome and its complications demands
rapid evaluation of new and accessible interventions. Insulin resistance is the central …
rapid evaluation of new and accessible interventions. Insulin resistance is the central …
Protection from Metabolic Dysregulation, Obesity, and Atherosclerosis by Citrus Flavonoids: Activation of Hepatic PGC1α‐Mediated Fatty Acid Oxidation
EE Mulvihill, MW Huff - PPAR research, 2012 - Wiley Online Library
Studies in a multitude of models including cell culture, animal and clinical studies
demonstrate that citrus‐derived flavonoids have therapeutic potential to attenuate …
demonstrate that citrus‐derived flavonoids have therapeutic potential to attenuate …
Grape seed proanthocyanidins correct dyslipidemia associated with a high-fat diet in rats and repress genes controlling lipogenesis and VLDL assembling in liver
H Quesada, JM Del Bas, D Pajuelo, S Díaz… - International journal of …, 2009 - nature.com
Objective: To determine whether proanthocyanidins can protect against dyslipidemia
induced by a high-fat diet (HFD) and to address the mechanisms that underlie this …
induced by a high-fat diet (HFD) and to address the mechanisms that underlie this …
Citrus flavonoids and lipid metabolism
JM Assini, EE Mulvihill, MW Huff - Current opinion in lipidology, 2013 - journals.lww.com
These recent studies suggest an important role of citrus flavonoids in the treatment of
dyslipidemia, insulin resistance, hepatic steatosis, obesity and atherosclerosis. The …
dyslipidemia, insulin resistance, hepatic steatosis, obesity and atherosclerosis. The …
Combination of citrus polymethoxyflavones, green tea polyphenols, and Lychee extracts suppresses obesity and hepatic steatosis in high‐fat diet induced obese mice
MH Pan, G Yang, S Li, MY Li, ML Tsai… - Molecular nutrition & …, 2017 - Wiley Online Library
Scope SlimTrym® is a formulated product composed of citrus polymethoxyflavones (PMFs),
green tea extract, and lychee extract. We investigated the effect of dietary SlimTrym® on diet …
green tea extract, and lychee extract. We investigated the effect of dietary SlimTrym® on diet …