Purpose: Pulmonary inflammation is associated with a variety of diseases. Assessing
pulmonary inflammation on in vivo imaging may facilitate the early detection and treatment …

Pulmonary diseases, a leading cause of morbidity and mortality, profoundly affect lung
tissue structure, resulting in alterations in mechanical and viscoelastic properties. However …

Although asthma is characterized as an inflammatory disease, recent reports highlight the
importance of pulmonary physiology outcome measures to the clinical assessment of …

Micro-computed tomography derived functional biomarkers used in lung disease research
can significantly complement end-stage histomorphometric measures while also allowing for …

During breathing, lung inflation is a dynamic process involving a balance of mechanical
factors, including transpulmonary pressure gradients, tissue compliance and airway …

Many lung disease processes are characterized by structural and functional heterogeneity
that is not directly appreciable with traditional physiological measurements. Experimental …

Here we report a tracking X-ray microscopy (TrXM) as a novel methodology by using upper
right lung apices alveoli in live intact mice. By enabling tracking of individual alveolar …

Computed tomography (CT) and spirometry are the mainstays of clinical pulmonary
assessment. Spirometry is effort dependent and only provides a single global measure that …

The pulmonary (or respiratory) system is responsible for gas exchange between the external
environment and the circulating blood supply in the body. The respiratory system contains a …

studies on normal physiological and pathological processes that take place in the lung are
hampered by the architecture and behavior of a living, breathing lung with a very complex …