Inflammation and Parkinson's disease pathogenesis: mechanisms and therapeutic insight

G Forloni, P La Vitola, M Cerovic, C Balducci - Progress in molecular …, 2021 - Elsevier
Abstract After Alzheimer's disease, Parkinson's disease is the most frequent
neurodegenerative disorder. Although numerous treatments have been developed to control …

Insights into neuroinflammation in Parkinson's disease: from biomarkers to anti‐inflammatory based therapies

NP Rocha, AS De Miranda… - BioMed research …, 2015 - Wiley Online Library
Parkinson's disease (PD) is the second most common neurodegenerative disorder
worldwide, being characterized by the progressive loss of dopaminergic neurons in the …

The potential role of neuroinflammation and transcription factors in Parkinson disease

PC Tiwari, R Pal - Dialogues in clinical neuroscience, 2017 - Taylor & Francis
Parkinson disease (PD) is a neurodegenerative disorder characterized by dopaminergic
neurons affected by inflammatory processes. Post-mortem analyses of brain and …

The role of Toll-like receptors and neuroinflammation in Parkinson's disease

A Heidari, N Yazdanpanah, N Rezaei - Journal of Neuroinflammation, 2022 - Springer
Background Parkinson's disease (PD) is the second most prevalent neurodegenerative
disorder, characterized by motor and non-motor symptoms, significantly affecting patients' …

Neuroinflammation in Parkinson's disease

JK Lee, T Tran, MG Tansey - Journal of Neuroimmune Pharmacology, 2009 - Springer
During the last two decades, a wealth of animal and human studies has implicated
inflammation-derived oxidative stress and cytokine-dependent neurotoxicity in the …

Neurodegeneration and neuroinflammation in Parkinson's disease: a self-sustained loop

G Arena, K Sharma, G Agyeah, R Krüger… - Current Neurology and …, 2022 - Springer
Abstract Purpose of Review Neuroinflammation plays a significant role in Parkinson's
disease (PD) etiology along with mitochondrial dysfunction and impaired proteostasis. In this …

Neuroinflammation and Parkinson's disease—From neurodegeneration to therapeutic opportunities

B Araújo, R Caridade-Silva, C Soares-Guedes… - Cells, 2022 - mdpi.com
Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder
worldwide. Clinically, it is characterized by a progressive degeneration of dopaminergic …

Inflammation in Parkinson's disease: mechanisms and therapeutic implications

M Pajares, A I. Rojo, G Manda, L Boscá, A Cuadrado - Cells, 2020 - mdpi.com
Parkinson's disease (PD) is a common neurodegenerative disorder primarily characterized
by the death of dopaminergic neurons that project from the substantia nigra pars compacta …

Neurodegeneration and inflammation—an interesting interplay in Parkinson's disease

C Marogianni, M Sokratous, E Dardiotis… - International journal of …, 2020 - mdpi.com
Parkinson's disease (PD) is a neurodegenerative disorder, caused by, so far, unknown
pathogenetic mechanisms. There is no doubt that pro-inflammatory immune-mediated …

The interplay between neuroinflammatory pathways and Parkinson's disease

P Eser, E Kocabicak, A Bekar, Y Temel - Experimental Neurology, 2023 - Elsevier
Parkinson's disease, a progressive neurodegenerative disorder predominantly affecting
elderly, is marked by the gradual degeneration of the nigrostriatal dopaminergic pathway …