Peripheral immunity, immunoaging and neuroinflammation in Parkinson's disease

N Kustrimovic, F Marino… - Current Medicinal …, 2019 - ingentaconnect.com
Parkinson's disease (PD) is the second most common neurodegenerative disorder among
elderly population, characterized by the progressive degeneration of dopaminergic neurons …

Updates on immunity and inflammation in Parkinson disease pathology

N Joshi, S Singh - Journal of neuroscience research, 2018 - Wiley Online Library
Studies in the last decade have suggested the association of both neuroinflammatory
processes and immune responses in Parkinson disease (PD) pathology. PD pathology is …

An inflammatory pathomechanism for Parkinson's disease?

C Wersinger, A Sidhu - Current medicinal chemistry, 2006 - ingentaconnect.com
Parkinson's disease (PD) is a slowly progressive neurodegenerative disorder characterized
by the loss of dopaminergic neurons in the Substantia Nigra pars compacta (SNpc), striatal …

Inflammation in Parkinson's disease

KU Tufekci, R Meuwissen, S Genc, K Genc - Advances in protein chemistry …, 2012 - Elsevier
Parkinson's disease (PD) is a common neurodegenerative disease that is characterized by
the degeneration of dopaminergic neurons in the substantia nigra pars compacta …

[HTML][HTML] The role of immune dysfunction in Parkinson's disease Development

D Cossu, T Hatano, N Hattori - International Journal of Molecular …, 2023 - mdpi.com
Recent research has unveiled intriguing insights suggesting that the body's immune system
may be implicated in Parkinson's disease (PD) development. Studies have observed …

[HTML][HTML] Peripheral Inflammation Enhances Microglia Response and Nigral Dopaminergic Cell Death in an in vivo MPTP Model of Parkinson's Disease

I García-Domínguez, K Veselá… - Frontiers in cellular …, 2018 - frontiersin.org
The impact of systemic inflammation in nigral dopaminergic cell loss remains unclear. Here,
we have investigated the role of peripheral inflammation induced by systemic …

Neuroinflammation in Parkinson's disease: its role in neuronal death and implications for therapeutic intervention

MG Tansey, MS Goldberg - Neurobiology of disease, 2010 - Elsevier
Parkinson's disease (PD) is the second most common neurodegenerative disease, after
Alzheimer's disease. The potential causes of PD remain uncertain, but recent studies …

[HTML][HTML] Brain microglia activation and peripheral adaptive immunity in Parkinson's disease: a multimodal PET study

SY Liu, HW Qiao, TB Song, XL Liu, YX Yao… - Journal of …, 2022 - Springer
Background Abnormal activation of immune system is an important pathogenesis of
Parkinson's disease, but the relationship between peripheral inflammation, central microglia …

Current opinions and perspectives on the role of immune system in the pathogenesis of Parkinson's disease

M Antonietta Panaro, A Cianciulli - Current Pharmaceutical …, 2012 - ingentaconnect.com
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the
degeneration of dopamine neurons in the substantia nigra pars compacta. To date, although …

Parkinson′ s disease and systemic inflammation

CC Ferrari, R Tarelli - Parkinson's disease, 2011 - Wiley Online Library
Peripheral inflammation triggers exacerbation in the central brain′ s ongoing damage in
several neurodegenerative diseases. Systemic inflammatory stimulus induce a general …