Glial‐mediated inflammation underlying parkinsonism

C Barcia - Scientifica, 2013 - Wiley Online Library
The interest in studying neuroimmune interactions is increasing in the scientific community,
and for many researchers, immunity is becoming a crucial factor in the understanding of the …

[HTML][HTML] Pathophysiology and Neuroimmune Interactions Underlying Parkinson's Disease and Traumatic Brain Injury

A Lillian, W Zuo, L Laham, S Hilfiker, JH Ye - International journal of …, 2023 - mdpi.com
Parkinson's disease (PD) is a progressive neurodegenerative disorder clinically defined by
motor instability, bradykinesia, and resting tremors. The clinical symptomatology is seen …

Roles of microglia in inflammation-mediated neurodegeneration: models, mechanisms, and therapeutic interventions for Parkinson's disease

HM Gao, D Tu, Y Gao, Q Liu, R Yang, Y Liu… - Advances in …, 2017 - Elsevier
Abstract Parkinson's disease (PD), the second most common neurodegenerative disease, is
characterized by a gradual, irreversible degeneration of the nigrostriatal dopaminergic …

[HTML][HTML] Cellular phenotypes as inflammatory mediators in Parkinson's disease: interventional targets and role of natural products

X Jiang, P Ganesan, T Rengarajan, DK Choi… - Biomedicine & …, 2018 - Elsevier
Pathogenesis of Parkinson's disease (PD) is undoubtedly a multifactorial phenomenon, with
diverse etiological agents. Pro-inflammatory mediators act as a skew that directs disease …

[HTML][HTML] Experimental models to study immune dysfunction in the pathogenesis of Parkinson's disease

J Saponjic, R Mejías, N Nikolovski, M Dragic… - International journal of …, 2024 - mdpi.com
Parkinson's disease (PD) is a chronic, age-related, progressive multisystem disease
associated with neuroinflammation and immune dysfunction. This review discusses the …

[HTML][HTML] Neuroinflammation in the pathophysiology of Parkinson's disease and therapeutic evidence of anti-inflammatory drugs

TB Bassani, MABF Vital, LK Rauh - Arquivos de neuro-psiquiatria, 2015 - SciELO Brasil
Parkinson's disease (PD) is the second most common neurodegenerative disease affecting
approximately 1.6% of the population over 60 years old. The cardinal motor symptoms are …

[HTML][HTML] Inflammation and immune dysfunction in Parkinson disease

MG Tansey, RL Wallings, MC Houser… - Nature Reviews …, 2022 - nature.com
Parkinson disease (PD) is a progressive neurodegenerative disease that affects peripheral
organs as well as the central nervous system and involves a fundamental role of …

[PDF][PDF] Inflammation and infection in Parkinsons disease

H Arai, T Furuya, Y Mizuno… - Histology and …, 2006 - digitum.um.es
The hallmark of Parkinson's disease (PD) is a specific degeneration of dopaminergic
neurons in the substantia nigra (SN). The cause of nigral dopaminergic neuronal cell death …

[HTML][HTML] Epigenetic regulation of neuroinflammation in Parkinson's disease

M Rasheed, J Liang, C Wang, Y Deng… - International Journal of …, 2021 - mdpi.com
Neuroinflammation is one of the most significant factors involved in the initiation and
progression of Parkinson's disease. PD is a neurodegenerative disorder with a motor …

The inflammatory response in the Parkinson brain

S Hunot, A Hartmann, EC Hirsch - Clinical Neuroscience Research, 2001 - Elsevier
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the
selective destruction of dopaminergic neurons in the mesencephalon. Other major …