The impact of blood on liver metabolite profiling–a combined metabolomic and proteomic approach
S Ly‐Verdú, A Schaefer, M Kahle… - Biomedical …, 2014 - Wiley Online Library
Metabolomics has entered the well‐established omic sciences as it is an indispensable
information resource to achieve a global picture of biological systems. The aim of the …
information resource to achieve a global picture of biological systems. The aim of the …
[HTML][HTML] Comparative targeted metabolomic profiles of porcine plasma and serum
Metabolomics has been used to characterise many biological matrices and obtain detailed
pictures of biological systems based on many metabolites. Plasma and serum are two blood …
pictures of biological systems based on many metabolites. Plasma and serum are two blood …
Systematic evaluation of serum and plasma collection on the endogenous metabolome
Z Zhou, Y Chen, J He, J Xu, R Zhang, Y Mao, Z Abliz - Bioanalysis, 2017 - Taylor & Francis
Aim: In metabolomics research, the use of different blood collection methods may influence
endogenous metabolites. Materials & methods: Ultra HPLC coupled with MS/MS was …
endogenous metabolites. Materials & methods: Ultra HPLC coupled with MS/MS was …
Serum UPLC-MS/MS metabolic profiling in an experimental model for acute-liver injury reveals potential biomarkers for hepatotoxicity
E Gonzalez, S van Liempd, J Conde-Vancells… - Metabolomics, 2012 - Springer
A key interest in clinical diagnosis and pharmaceutical industry is to have a repertoire of
noninvasive biomarkers to—individually or in combination—be able to infer or predict the …
noninvasive biomarkers to—individually or in combination—be able to infer or predict the …
[HTML][HTML] Metabolic profiling of body fluids and multivariate data analysis
Metabolome analyses of body fluids are challenging due pre-analytical variations, such as
pre-processing delay and temperature, and constant dynamical changes of biochemical …
pre-processing delay and temperature, and constant dynamical changes of biochemical …
Joint MS‐based platforms for comprehensive comparison of rat plasma and serum metabolic profiling
Z Lin, Z Zhang, H Lu, Y Jin, L Yi… - Biomedical …, 2014 - Wiley Online Library
Metabolomics is a rapidly growing field in the comprehensive understanding of cellular and
organism‐specific responses associated with perturbations induced by medicines …
organism‐specific responses associated with perturbations induced by medicines …
Procedure for tissue sample preparation and metabolite extraction for high-throughput targeted metabolomics
W Römisch-Margl, C Prehn, R Bogumil, C Röhring… - Metabolomics, 2012 - Springer
Reproducible quantification of metabolites in tissue samples is of high importance for
characterization of animal models and identification of metabolic changes that occur in …
characterization of animal models and identification of metabolic changes that occur in …
Differences in metabolite profiles caused by pre-analytical blood processing procedures
S Nishiumi, M Suzuki, T Kobayashi… - Journal of bioscience and …, 2018 - Elsevier
Recently, the use of metabolomic analysis of human serum and plasma for biomarker
discovery and disease diagnosis in clinical studies has been increasing. The feasibility of …
discovery and disease diagnosis in clinical studies has been increasing. The feasibility of …
[HTML][HTML] Important considerations for sample collection in metabolomics studies with a special focus on applications to liver functions
L Smith, J Villaret-Cazadamont, SP Claus, C Canlet… - Metabolites, 2020 - mdpi.com
Metabolomics has found numerous applications in the study of liver metabolism in health
and disease. Metabolomics studies can be conducted in a variety of biological matrices …
and disease. Metabolomics studies can be conducted in a variety of biological matrices …
[HTML][HTML] Impact of anesthesia and euthanasia on metabolomics of mammalian tissues: studies in a C57BL/6J mouse model
KA Overmyer, C Thonusin, NR Qi, CF Burant… - PloS one, 2015 - journals.plos.org
A critical application of metabolomics is the evaluation of tissues, which are often the primary
sites of metabolic dysregulation in disease. Laboratory rodents have been widely used for …
sites of metabolic dysregulation in disease. Laboratory rodents have been widely used for …