Abstract Background In Honduras, chloroquine and primaquine are recommended and still
appear to be effective for treatment of Plasmodium falciparum and Plasmodium vivax …

Background Scarce data are available on Plasmodium falciparum anti-malarial drug
resistance in Pakistan. The aim of this study was, therefore, to determine the prevalence of …

The potential role of polymorphisms in the pfcrt and pfmdr1 genes and in vitro susceptibility
to amodiaquine and desethylamodiaquine were explored in 15 chloroquine-resistant …

Background Few studies have been conducted in Pakistan to determine the efficacy of
chloroquine and sulphadoxine-pyrimethamine (SP), which remain in use as treatment for …

Abstract Background Since 2011, artesunate+ sulphadoxine-pyrimethamine (ASP), instead
of chloroquine, has been recommended for treatment of uncomplicated malaria in India. In …

Drug resistance against P. falciparum has been recognized as the crucial obstacle to
curbing mortality and morbidity from malaria. We therefore determined the baseline …

Two hundred and three Plasmodium falciparum isolates from Jazan area, southwest Saudi
Arabia, were typed for Pfcrt, Pfmdr1, dhps, and dhfr mutations associated with resistance to …

The extent of gene polymorphisms associated with resistance to chloroquine and
sulfadoxinepyrimethamine was examined in field isolates of Plasmodium falciparum from …

We determined the baseline frequency distribution of mutant alleles of genes associated
with resistance to chloroquine and sulfadoxine-pyrimethamine in Plasmodium falciparum …

Drug resistance is probably the greatest challenge to most malaria-control programs. Given
the limited resources for other malarial-control measures, rational drug used is crucial …