The programming power of the placenta

AN Sferruzzi-Perri, EJ Camm - Frontiers in physiology, 2016 - frontiersin.org
Size at birth is a critical determinant of life expectancy, and is dependent primarily on the
placental supply of nutrients. However, the placenta is not just a passive organ for the …

Placental adaptations supporting fetal growth during normal and adverse gestational environments

AN Sferruzzi‐Perri, J Lopez‐Tello… - Experimental …, 2023 - Wiley Online Library
The placenta is vital for mammalian development and a key determinant of life‐long health.
It is the interface between the mother and fetus and is responsible for transporting the …

[图书][B] The placenta and human developmental programming

GJ Burton, DJP Barker, A Moffett, K Thornburg - 2010 - books.google.com
Developmental programming is a rapidly advancing discipline of great importance to basic
scientists and health professionals alike. This text integrates, for the first time, contributions …

Biological features of placental programming

KL Thornburg, K Kolahi, M Pierce, A Valent, R Drake… - Placenta, 2016 - Elsevier
The placenta is a key organ in programming the fetus for later disease. This review outlines
nine of many structural and physiological features of the placenta which are associated with …

The placenta and intrauterine programming

AL Fowden, AJ Forhead, PM Coan… - Journal of …, 2008 - Wiley Online Library
Intrauterine programming is the process by which the structure and function of tissues are
altered permanently by insults acting during early development. In mammals, the placenta …

Placental adaptations to the maternal–fetal environment: implications for fetal growth and developmental programming

I Sandovici, K Hoelle, E Angiolini… - Reproductive biomedicine …, 2012 - Elsevier
The placenta is a transient organ found in eutherian mammals that evolved primarily to
provide nutrients for the developing fetus. The placenta exchanges a wide array of nutrients …

Placental dysfunction and fetal programming: the importance of placental size, shape, histopathology, and molecular composition

MS Longtine, DM Nelson - Seminars in reproductive medicine, 2011 - thieme-connect.com
Normal function of the placenta is pivotal for optimal fetal growth and development. Fetal
programming commonly is associated with placental dysfunction that predisposes to …

Placental efficiency and adaptation: endocrine regulation

AL Fowden, AN Sferruzzi‐Perri, PM Coan… - The Journal of …, 2009 - Wiley Online Library
Size at birth is critical in determining life expectancy and is dependent primarily on the
placental supply of nutrients. However, the fetus is not just a passive recipient of nutrients …

The placenta: transcriptional, epigenetic, and physiological integration during development

E Maltepe, AI Bakardjiev… - The Journal of clinical …, 2010 - Am Soc Clin Investig
The placenta provides critical transport functions between the maternal and fetal circulations
during intrauterine development. Formation of this interface relies on coordinated …

Placenta, evolution and lifelong health

RM Lewis, JK Cleal, MA Hanson - Placenta, 2012 - Elsevier
The intrauterine environment has an important influence on lifelong health, and babies who
grew poorly in the womb are more likely to develop chronic diseases in later life. Placental …