The enzyme tyrosine hydroxylase (TH) catalyzes the rate-limiting step in the biosynthesis of
catecholamines in dopaminergic and noradrenergic neurons of the brain, in sympathetic …

The enzyme tyrosine hydroxylase (TH) was immunohistochemically localized by the
peroxidase-antiperoxidase method in rat to chromaffin cells of the adrenal medulla, large …

Tyrosine hydroxylase (EC 1.14. 16.2), the enzyme catalyzing the rate-limiting step in
catecholamine biosynthesis, was localized by electron microscopy within noradrenergic …

The subcellular distribution of the protein tyrosine hydroxylase (TH) after fractionation of rat
brain tissue was studied by a sensitive technique of immunoblot quantification in the …

By using an antibody to human tyrosine hydroxylase (TH) in conjunction with the peroxidase-
anti-peroxidase (PAP) technique 12 we have found it possible to map catecholaminergic …

We sought to develop a quantitative immunocytochemical procedure using the peroxidase-
antiperoxidase (PAP) technique to analyze amounts of the neurotransmitter biosynthetic …

METHODS AND MATERIALS Rats (Holtzman strain; 175-200 g) were decapitated, and the
brains were rapidly removed and frozen on dry ice. The brains were thawed, placed on ice …

The enzyme, tyrosine hydroxylase (TH, EC 1.14. 16.3) catalyzes the rate limiting step in the
biosynthesis of catecholaminesL Because of difficulties in isolating the enzyme, the …

The catecholaminergic neurons of the nervous system have been studied histochemically
with fluorescent derivatives of catecholamines and immunocytochemically using antibodies …

A monospecific antibody against tyrosine hydroxylase (TH), purified from a transplantable rat
pheochromocytoma, was produced in rabbits. Immunohistochemical techniques were …