Identification of a novel splice acceptor in the HIV-1 genome: independent expression of the cytoplasmic tail of the envelope protein

B Berkhout, JLB Van Wamel - Archives of virology, 1996 - Springer
Multiple splicing sites exist in the RNA genome of the human immunodeficiency virus type 1
(HIV-1). In a screen for subgenomic forms of the HIV-1 genome that could be transferred to …

A naturally arising mutation of a potential silencer of exon splicing in human immunodeficiency virus type 1 induces dominant aberrant splicing and arrests virus …

MP Wentz, BE Moore, MW Cloyd, SM Berget… - Journal of …, 1997 - Am Soc Microbiol
We have isolated a naturally arising human immunodeficiency type 1 (HIV-1) mutant
containing a point mutation within the env gene. The point mutation resulted in complete …

Alternative splicing of human immunodeficiency virus type 1 mRNA modulates viral protein expression, replication, and infectivity

DF Purcell, MA Martin - Journal of virology, 1993 - Am Soc Microbiol
Multiple RNA splicing sites exist within human immunodeficiency virus type 1 (HIV-1)
genomic RNA, and these sites enable the synthesis of many mRNAs for each of several viral …

Human immunodeficiency virus env expression becomes Rev-independent if the env region is not defined as an intron

ML Hammarskjöld, H Li, D Rekosh, S Prasad - Journal of virology, 1994 - Am Soc Microbiol
The human immunodeficiency virus (HIV) Rev protein functions to facilitate export of intron-
containing HIV mRNA from the nucleus to the cytoplasm. We have previously shown that …

Characterization of a nuclear retention sequence within the 3′ region of the HIV-2 envelope gene

R Keller, L Montagnier, A Cordonnier - Virology, 1993 - Elsevier
During the phenotypic analysis of mutations in the HIV-2 envelope protein (gp140), we have
identified a mutant that expresses high levels of gp140 in the absence of the Rev protein …

Simian immunodeficiency virus displays complex patterns of RNA splicing

GA Viglianti, PL Sharma, JI Mullins - Journal of virology, 1990 - Am Soc Microbiol
The human and simian immunodeficiency viruses encode at least six gene products that
apparently serve regulatory functions. To evaluate the regulation of simian …

Regulation of HIV-1 alternative RNA splicing and its role in virus replication

CM Stoltzfus - Advances in virus research, 2009 - Elsevier
Over 40 different human immunodeficiency virus type 1 (HIV-1) mRNA species, both
completely and incompletely spliced, are produced by alternative splicing of the primary viral …

Overlapping Cis Sites Used for Splicing of HIV-1env/nefand revmRNAs

AK Swanson, CM Stoltzfus - Journal of Biological Chemistry, 1998 - ASBMB
Alternative splicing is used to generate more than 30 human immunodeficiency virus type 1
(HIV-1) spliced and unspliced mRNAs from a single primary transcript. The abundance of …

Human immunodeficiency virus type 1 splicing at the major splice donor site is controlled by highly conserved RNA sequence and structural elements

N Mueller, B Klaver, B Berkhout… - Journal of General …, 2015 - microbiologyresearch.org
Human immunodeficiency virus type 1 (HIV-1) splicing has to be strictly controlled to ensure
the balanced production of the unspliced and all differently spliced viral RNAs. Splicing at …

Non-Coding RNA Features Critical to the Replication of HIV-1

MA Takata - 2019 - digitalcommons.rockefeller.edu
The HIV-1 genome contains RNA sequences and structures that control many aspects of
viral replication including, but not limited to transcription, splicing, nuclear export, translation …